391678-36-7 Usage
Description
3-Butynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) is a complex chemical compound derived from butynoic acid, featuring a carbamate group and a chiral carbon atom that results in two enantiomers. 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) is notable for its potential applications in pharmaceuticals and medicinal chemistry, driven by its unique structural attributes and possible biological activities. The chiral center and the carbamate group contribute to its significance in asymmetric synthesis and drug development, as well as its potential for chemical reactivity and interaction with biological targets.
Uses
Used in Pharmaceutical Industry:
3-Butynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological activities and unique structural features. The chiral carbon atom allows for the development of enantiomer-specific drugs, which can have different effects and potencies in biological systems.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-Butynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) serves as a valuable compound for studying the effects of chirality on drug action and metabolism. Its structure is exploited in the design of novel drugs with improved efficacy and selectivity.
Used in Asymmetric Synthesis:
3-Butynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) is utilized as a building block in asymmetric synthesis, where the chiral center plays a crucial role in creating enantiomerically pure compounds. This is particularly important in the production of pharmaceuticals, where the desired biological activity may be associated with only one enantiomer.
Used in Drug Design:
3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-,(2S)-(9CI) is also used in drug design for its potential to interact with biological targets due to the presence of the carbamate group. This group can be modified to enhance the compound's affinity and selectivity for specific receptors or enzymes, leading to the development of more effective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 391678-36-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,1,6,7 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 391678-36:
(8*3)+(7*9)+(6*1)+(5*6)+(4*7)+(3*8)+(2*3)+(1*6)=187
187 % 10 = 7
So 391678-36-7 is a valid CAS Registry Number.
391678-36-7Relevant articles and documents
Amino alcohol derivatives
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Page 114, (2010/11/30)
Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives: wherein R1 and R2 are a hydrogen atom, an amino protecting group; R3 is a hydrogen atom, a hydroxy protecting group; R4 is a lower alkyl group; n is an integer from 1 to 6; X is an ethylene group; Y is a C1-C10 alkylene group, a C1-C10 alkylene group substituted with 1 to 3 substituents selected from substituent group a and b; R5 is an aryl group; R6 and R7 are a hydrogen atom, a group selected from substituent group a; with the proviso when R5 is a hydrogen atom, Y is not a single bond or a straight chain C1-C10 alkylene group.
A straightforward synthesis of both enantiomers of α-vinylalanine and α-ethynylalanine
Avenoza, Alberto,Cativiela, Carlos,Peregrina, Jesus M.,Sucunza, David,Zurbano, Maria M.
, p. 4653 - 4661 (2007/10/03)
This report describes the synthesis of enantiomerically pure (S)- and (R)-α-vinylalanines and (S)- and (R)-α-ethynylalanines, four quaternary α- amino acids, using a straightforward synthetic route and starting from (S)- and (R)-N-Boc-N,O-isopropylidene-α-methylserinals. (C) 1999 Elsevier Science Ltd.
