3917-29-1

Upstream product

• 37609-34-0 cyclohex-1-en-1-yllithium 
• 1192-88-7 1-cyclohexene-1-carboxaldehyde 
• 18448-47-0 methyl cyclohex-1-ene-1-carboxylate 
• 636-82-8 cyclohexene-1-carboxylic acid 
• 111-34-2 -butyl vinyl ether 
• 4845-04-9 1-cyclohexene-1-methanol 
• 109-92-2 ethyl vinyl ether 
• 3917-04-2 <2-Chlor-aethyl>--aether 

Downstream Products

• 3991-38-6 2-(2-methylenecyclohexyl)acetaldehyde 
• 53544-46-0 2-(1-methylenecyclohex-2-yl)ethan-1-ol 
• 343974-48-1 (+/-)-1-(2-iodoethyl)-2-methylenecyclohexane 
• 869101-47-3 (1R,3aR,5R,7aR)-1-((R)-1,5-Dimethyl-hexyl)-7a-methyl-5-[2-(2-methylene-cyclohexyl)-ethyl]-octahydro-inden-4-one 
• 343974-40-3 (1R,3aR,4S,5R,7aR)-4-Allyl-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-5-[2-(2-methylene-cyclohexyl)-ethyl]-octahydro-inden-4-ol 

Relevant academic research and scientific papers

RCM for the construction of novel steroid-like polycyclic systems. 1. Studies on the synthesis of a PreD3-D3 transition state analogue

Natural and nonnatural polycyclic systems containing eight-membered carbocycles constitute a large class of compounds of importance in organic chemistry, biology, and medicine. Here we describe a new strategy by which complex polycyclic steroid-like systems can be constructed on the steroid CD framework, by a combination of RCM and Heck cyclizations. The method is exemplified by its application to the stereoselective synthesis of 6-8-6 fused carbocyclic systems that mimic the putative transition structure of the isomerization of previtamin D3 to vitamin D3.

X=Y-ZH Systems as potential 1,3-dipoles. Part 52: Fused-ring forming electrophile induced oxime→nitrone→cycloaddition cascades

Electrophile induced cyclisation of oximes onto endocyclic alkenes and exo-methylene cycloalkanes occurs stereo- and regio-specifically generating cis-fused bicyclic nitrones in good yield. Subsequent facially selective cycloaddition with N-methylmaleimid