391902-36-6Relevant articles and documents
Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics
Jia,Ye,Dinaut,Wang,Waddleton,Payette,Ramachandran,Kennedy,Hum,Taylor
, p. 4584 - 4594 (2007/10/03)
Protein tyrosine phosphatases (PTPases) are signal-transducing enzymes that dephosphorylate intracellular proteins that have phosphorylated tyrosine residues. It has been demonstrated that protein tyrosine phosphatase 1B (PTP1B) is an attractive therapeut