3-Nitro-2,4,6-trimethylbenzenesulfonyl fluoride, also known as 3-nitro-2,4,6-trimethylbenzenesulfonyl fluoride or NTMBSF, is a chemical compound with the molecular formula C9H10FNO4S2. It is a derivative of benzenesulfonyl fluoride, featuring a nitro group at the 3-position and three methyl groups at the 2, 4, and 6 positions. NTMBSF is a potent and selective inhibitor of serine proteases, particularly trypsin and thrombin, making it useful in various biochemical and pharmaceutical applications. It is often used as a reagent in the study of protease activity and as a tool to investigate the role of proteases in biological processes. The compound is typically synthesized through a series of chemical reactions involving the substitution of functional groups on the benzene ring and the introduction of the sulfonyl fluoride group. NTMBSF is a white crystalline solid that is soluble in organic solvents and has a relatively high melting point. Due to its reactivity and potential toxicity, it is important to handle NTMBSF with care and in accordance with proper safety protocols.
The CAS Registry Mumber 392-49-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 2 respectively; the second part has 2 digits, 4 and 9 respectively. Calculate Digit Verification of CAS Registry Number 392-49: (5*3)+(4*9)+(3*2)+(2*4)+(1*9)=74 74 % 10 = 4 So 392-49-4 is a valid CAS Registry Number.