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1-p-Bromphenyl-2-nitropropan-1-ol is a chemical compound with the molecular formula C9H10BrNO3. It is a derivative of propanol, featuring a nitro group at the 2nd carbon and a p-bromophenyl group attached to the 1st carbon. 1-p-Bromphenyl-2-nitropropan-1-ol is characterized by its yellowish color and is soluble in organic solvents. It is primarily used in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and reactivity. The presence of both a nitro group and a halogenated aromatic ring makes it a versatile intermediate in organic chemistry, particularly in the preparation of various drugs and agrochemicals.

39220-95-6

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39220-95-6 Usage

Chemical group

Alkylphenols
Belongs to a group of organic compounds with a phenyl ring and an alkyl side chain

Molar mass

259.08 g/mol
The mass of one mole of the compound

Usage

Antihistamine and decongestant
Commonly used in the treatment of allergy symptoms

Mechanism of action

Blocks the effects of histamine
Reduces symptoms such as sneezing, itching, watery eyes, and runny nose

Additional property

Dries up nasal passages and relieves congestion
Helps to alleviate nasal congestion

Chemical structure

Bromine-substituted phenyl ring, nitro group, and propanol group
Key components that contribute to its pharmacological activity

Role

Management of allergic reactions and related conditions
Plays a crucial role in treating and managing allergy symptoms and related health issues

Check Digit Verification of cas no

The CAS Registry Mumber 39220-95-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,2 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 39220-95:
(7*3)+(6*9)+(5*2)+(4*2)+(3*0)+(2*9)+(1*5)=116
116 % 10 = 6
So 39220-95-6 is a valid CAS Registry Number.

39220-95-6Relevant academic research and scientific papers

Pore size control and organocatalytic properties of nanostructured silica hybrid materials containing amino and ammonium groups

El Hankari, Samir,Motos-Perez, Blanca,Hesemann, Peter,Bouhaouss, Ahmed,Moreau, Joel J. E.

experimental part, p. 6948 - 6955 (2011/11/28)

Periodic mesoporous organosilicas containing amine and ammonium substructures were synthesized via soft templating approaches using anionic surfactants. Pore size control was achieved either using anionic surfactants containing alkyl groups of variable chain lengths or by addition of swelling agents such as mesitylene (1,3,5-trimethylbenzene, TMB) to the hydrolysis-polycondensation mixture. The addition of mesitylene allows to increase the pore size in the materials from 2 to 6 nm. The materials appear as versatile and recyclable heterogeneous organocatalysts in Knoevenagel and Henry reactions and in the formation of monoglycerides by ring opening reaction of glycidol. This study highlights the huge potential of silica hybrid materials containing ionic substructures (i-silica) materials in heterogeneous catalysis.

SiO2 Catalyzed Henry Reaction: Microwave Assisted Preparation of 2-Nitroalkanols in Dry Media

Kumar, H. M. Sampath,Reddy, B. V. Subba,Yadav, J. S.

, p. 637 - 638 (2007/10/03)

Nitroalkanes undergo rapid addition to aromatic aldehydes (Henry reaction) on the surface of activated SiO2, when irradiated with microwave, to afford 2-nitroalkanols in moderate to high yields.

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