392330-57-3Relevant academic research and scientific papers
Synthesis of conformationaly preorganized and cell-permeable guanidine-based γ-peptide nucleic acids (γGPNAs)
Sahu, Bichismita,Chenna, Venugopal,Lathrop, Kira L.,Thomas, Sufi M.,Zon, Gerald,Livak, Kenneth J.,Ly, Danith H.
experimental part, p. 1509 - 1516 (2009/07/25)
A general method for preparing optically pure guanidine-based y-peptide nucleic acid (γGPNA) monomers for all four natural nucleobases (A, C, G, and T) is described. These second-generation γGPNAs differ from the first-generation GPNAs in that the guanidi
Discovery of sulfonylalkylamides: A new class of orally active factor Xa inhibitors
Imaeda, Yasuhiro,Miyawaki, Toshio,Sakamoto, Hiroki,Itoh, Fumio,Konishi, Noriko,Hiroe, Katsuhiko,Kawamura, Masaki,Tanaka, Toshimasa,Kubo, Keiji
, p. 2243 - 2260 (2008/12/20)
Factor Xa (FXa) is a trypsin-like serine protease involved in the coagulation cascade and has received great interest as a potential target for the development of new antithrombotic agents. Most of amidine-type FXa inhibitors reported have been found to s
