392336-40-2

Upstream product

• 392336-68-4 2-[(1RS,4E)-6-(tert-butyldimethylsilanyloxy)-1-(tert-butyldiphenylsilanyloxy)-4-methylhex-4-enyl]thiophene 
• 392336-38-8 (2E,4E,8RS)-8-(tert-butyldimethylsilanyloxy)-5-methyl-8-thiophen-2-ylocta-2,4-dienoic acid ethyl ester 
• 392336-39-9 (2E,4E,8RS)-8-(tert-butyldimethylsilanyloxy)-5-methyl-8-thiophen-2-ylocta-2,4-dien-1-ol 

Downstream Products

• 392336-41-3 3,4,5-trimethoxybenzaldehyde O-[(2E,4E,8RS)-8-(tert-butyldiphenylsilanyloxy)-5-methyl-8-thiophen-2-ylocta-2,4-dienyl]oxime 

Relevant academic research and scientific papers

Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A

Structure-activity relationship analysis of synthetic analogues of curacin A revealed the lack of activity of traditional heterocyclic replacements of the thiazoline ring or cyclopropyl analogues of the core diene segment. The significance of the C(3)-C(4