39234-86-1

Usage

Chemical Properties

White to Yellow crystal or powder

InChI:InChI=1/C4ClF5/c5-1(3(7)8)2(6)4(9)10

Upstream product

• 328-74-5 3,5-Bis-(trifluoromethyl)aniline 

Downstream Products

• 111711-53-6 1-(3,5-Bis-trifluoromethyl-benzenesulfonyl)-5-ethoxy-pyrrolidin-2-one 
• 119481-42-4 N-[3-(Quinolin-2-ylmethoxy)-phenyl]-3,5-bis-trifluoromethyl-benzenesulfonamide 
• 112424-06-3 (1α,2β,3β,4α,5α,6α)-5,6-Epoxy-2,3-S-(1,2-phenylen)-2,3-dithio-1,2,3,4-cyclohexantetrol-1,4-bis<3,5-bis(trifluormethyl)benzolsulfonat> 
• 112424-10-9 (1α,2α,3α,4α,5β,6β)-1,2:3,4-Bis-S-(1,2-phenylen)-1,2,3,4-tetrathio-1,2,3,4,5,6-cyclohexanhexol-5,6-bis-<3,5-bis(trifluormethyl)benzolsulfonat> 
• 80953-39-5 C₁₆H₆F₁₂O₆S₂ 
• 155134-49-9 (1R,2R)-1,2-bis(3,5-trifluoromethylbenzenesulfonylamino)cyclohexane 
• 39213-22-4 3,5-bis(trifluoromethyl)benzenesulfonamide 
• 237750-86-6 4-[(5-(3,5-Bis-trifluoromethylphenylsulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile 
• 652150-79-3 (S)-N-[3,5-(bistrifluoromethyl)benzenesulfonyl]-2-isopropylaziridine 
• 800378-43-2 (S)-N-[3,5-bis(trifluoromethyl)benzenesulfonyl]-2-tert-butylaziridine 
• 1053742-45-2 C₄₉H₄₄F₆O₁₀S 
• 920982-38-3 [9-(3,5-bis-trifluoromethyl-benzenesulfonyl)-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-72-5 [9-(3,5-bis-trifluoromethyl-benzenesulfonyl)-6-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 918547-63-4 BSc₂₄₁₀ 

Relevant academic research and scientific papers

Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

A new flow procedure for the preparation of arylsulfonyl chlorides from aniline starting materials is described. The reaction conditions are mild, requiring no added acid and are amenable to continuous flow processing, in a safe, easily scalable and less labour intensive way than the corresponding batch method.

NEW PROCESS FOR ENANTIOSELECTIVE NUCLEOPHILIC ADDITION TO ALDEHYDES TO FORM SECONDARY ALCOHOLS

New methodology is described for the enantioselective conversion of aldehydes to anti aldols 4 and homoallylic alcohols 7.

Transition-State Structures of Base-Promoted, Imine-Forming Eliminations from N-Benzyl-O-(arylsulfonyl)hydroxylamines

Eliminations in XC6H4CH2NHOSO2C6H4Y promoted by amine bases were examined in 2.25 M H2O in THF-EtOAc (3:1) and methanol.Transition-state parameters in methanol were found to be ρ = 0.11, kH/kD = 1.2, for the benzylic group and ρ = 1.65 for the leaving group.These data indicate that the polar solvent methanol causes an E1-like transition state in this elimination.Broensted parameters were determined for both solvent and found to be α = 0.3 and β = 2.32 for the former and α = 0.1 and β = 2.65 for methanol.These parameters can be used to map the transition-state structure in a More-O'Ferral-Jencks diagram.Values of β1g for a variety of reactions are found to be a useful gauge of reaction type and leaving group loss in the transition state.