39234-86-1

Basic information

• Product Name: 3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE
• Synonyms: 3,5-Bis(trifluoromethyl)benzenesulfonyl chloride, 97+%;3,5-Bis(trifluoromethyl)benzenesulphonyl chloride 97%;3,5-Bis(trifluoromethyl)benzenesulphonylchloride97%;3,5-bis(trimethyl)benzenesulfonyl chloride;3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 96%;3,5-Bis(trifluoromethyl)benzenesulfonyl chlorideloride;3,5-Bis(trifluoromethyl)benzenesulfonic acid chloride;{[3,5-bis(trifluoroMethyl)benzene]sulfonyl}chloranuide
• CAS NO: 39234-86-1
• Molecular Formula: C₈H₃ClF₆O₂S
• Molecular Weight: 312.62
• EINECS: 254-371-0
• Product Categories: Fluorobenzene;Benzenesulfonyl chloride;Miscellaneous;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Fluorine series
• Mol File: 39234-86-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 34-38 °C(lit.)
• Boiling Point: 70°C 2mm
• Flash Point: 228 °F
• Appearance: /
• Density: 1.618 g/cm³
• Vapor Pressure: 1070mmHg at 25°C
• Refractive Index: 1.349
• Storage Temp.: Refrigerator
• Solubility: soluble in Toluene
• Sensitive: Hygroscopic
• BRN: 3621218
• CAS DataBase Reference: 3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(39234-86-1)
• EPA Substance Registry System: 3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE(39234-86-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 39234-86-1(Hazardous Substances Data)

Usage

Chemical Properties

White to Yellow crystal or powder

InChI:InChI=1/C4ClF5/c5-1(3(7)8)2(6)4(9)10

Upstream product

• 328-74-5 3,5-Bis-(trifluoromethyl)aniline 

Downstream Products

• 111711-53-6 1-(3,5-Bis-trifluoromethyl-benzenesulfonyl)-5-ethoxy-pyrrolidin-2-one 
• 119481-42-4 N-[3-(Quinolin-2-ylmethoxy)-phenyl]-3,5-bis-trifluoromethyl-benzenesulfonamide 
• 112424-06-3 (1α,2β,3β,4α,5α,6α)-5,6-Epoxy-2,3-S-(1,2-phenylen)-2,3-dithio-1,2,3,4-cyclohexantetrol-1,4-bis<3,5-bis(trifluormethyl)benzolsulfonat> 
• 112424-10-9 (1α,2α,3α,4α,5β,6β)-1,2:3,4-Bis-S-(1,2-phenylen)-1,2,3,4-tetrathio-1,2,3,4,5,6-cyclohexanhexol-5,6-bis-<3,5-bis(trifluormethyl)benzolsulfonat> 
• 80953-39-5 C₁₆H₆F₁₂O₆S₂ 
• 155134-49-9 (1R,2R)-1,2-bis(3,5-trifluoromethylbenzenesulfonylamino)cyclohexane 
• 39213-22-4 3,5-bis(trifluoromethyl)benzenesulfonamide 
• 237750-86-6 4-[(5-(3,5-Bis-trifluoromethylphenylsulphonylamino)-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile 
• 652150-79-3 (S)-N-[3,5-(bistrifluoromethyl)benzenesulfonyl]-2-isopropylaziridine 
• 800378-43-2 (S)-N-[3,5-bis(trifluoromethyl)benzenesulfonyl]-2-tert-butylaziridine 
• 1044266-21-8 C₁₄H₇Cl₂F₆NO₃S 
• 1044266-12-7 C₁₄H₇F₈NO₂S 
• 1013491-92-3 C₁₄H₇F₈NO₂S 
• 491861-53-1 C₁₄H₇F₈NO₂S 

Relevant articles and documents

Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

A new flow procedure for the preparation of arylsulfonyl chlorides from aniline starting materials is described. The reaction conditions are mild, requiring no added acid and are amenable to continuous flow processing, in a safe, easily scalable and less labour intensive way than the corresponding batch method.

NEW PROCESS FOR ENANTIOSELECTIVE NUCLEOPHILIC ADDITION TO ALDEHYDES TO FORM SECONDARY ALCOHOLS

New methodology is described for the enantioselective conversion of aldehydes to anti aldols 4 and homoallylic alcohols 7.