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Pyrazolam is a benzodiazepine derivative characterized by its sedative and anxiolytic properties. It modulates the GABA receptors in the central nervous system, inducing a calming and relaxing effect on the user. Recognized for its potential as an anxiolytic and hypnotic agent, Pyrazolam has attracted interest in both research and recreational drug communities.

39243-02-2

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39243-02-2 Usage

Uses

Used in Pharmaceutical Industry:
Pyrazolam is used as an anxiolytic agent for its ability to alleviate anxiety and stress by interacting with the GABA receptors in the central nervous system, providing a sense of calm and relaxation.
Used in Sleep Aid Applications:
Pyrazolam is utilized as a hypnotic agent to promote sleep and improve sleep quality, particularly for individuals experiencing insomnia or other sleep disorders. Its sedative effects help to induce a state of drowsiness and facilitate a more restful sleep.
Used in Research:
In the scientific community, Pyrazolam is used for studying the effects of benzodiazepines on the central nervous system and their potential therapeutic applications in various conditions related to anxiety and sleep disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 39243-02-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,4 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 39243-02:
(7*3)+(6*9)+(5*2)+(4*4)+(3*3)+(2*0)+(1*2)=112
112 % 10 = 2
So 39243-02-2 is a valid CAS Registry Number.

39243-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]be nzodiazepine

1.2 Other means of identification

Product number -
Other names Flubromazolam

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:39243-02-2 SDS

39243-02-2Synthetic route

triethyl-orthoacetate

triethyl-orthoacetate

7-bromo-5-(pyridin-2-yl)-3H-1,4-benzodiazepin-2-yl hydrazine
40890-40-2

7-bromo-5-(pyridin-2-yl)-3H-1,4-benzodiazepin-2-yl hydrazine

pyrazolam
39243-02-2

pyrazolam

Conditions
ConditionsYield
With toluene-4-sulfonic acid In ethanol
pyrazolam
39243-02-2

pyrazolam

A

[5-bromo-2-(3-chloromethyl-[1,2,4]triazol-4-yl)-phenyl]-pyridin-2-yl-methanone
58765-77-8

[5-bromo-2-(3-chloromethyl-[1,2,4]triazol-4-yl)-phenyl]-pyridin-2-yl-methanone

B

[5-bromo-2-(3-hydroxymethyl-5-methyl-[1,2,4]triazol-4-yl)-phenyl]-pyridin-2-yl-methanone
58765-78-9

[5-bromo-2-(3-hydroxymethyl-5-methyl-[1,2,4]triazol-4-yl)-phenyl]-pyridin-2-yl-methanone

Conditions
ConditionsYield
With sodium nitrite In 6 N-hydrochloric acid; water
pyrazolam
39243-02-2

pyrazolam

8-Bromo-1-(2-hydroxyethyl)-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine

8-Bromo-1-(2-hydroxyethyl)-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene
pyrazolam
39243-02-2

pyrazolam

8-bromo-N,N-dimethyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-1-ethanamine
40988-19-0

8-bromo-N,N-dimethyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-1-ethanamine

Conditions
ConditionsYield
In N-methyl-acetamide; bis-(dimethylamino)methane

39243-02-2Relevant academic research and scientific papers

Preparation of triazolo benzodiazepines and novel compounds

-

, (2008/06/13)

Novel preparations of triazolobenzodiazepines are disclosed. Novel 6-pyridyl-4H-triazolo[4,3-a]-1,4-benzodiazepines and novel intermediates are also disclosed which are useful as anti-convulsants, muscle relaxants and sedative agents.

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