392674-82-7

Upstream product

• 185414-14-6 cis-3-allyloxy-2-azetidinone 
• 392674-93-0 (3-Methyl-but-2-enyloxy)-acetyl chloride 
• 103239-04-9 N-(p-anisyl)-4-<(S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>-methylene-imine 

Downstream Products

• 392675-15-9 (+)-(3R,4R)-4-formyl-1-(4-methoxyphenyl)-3-(3'-methyl-2'-butenyloxy)-2-azetidinone 
• 392675-03-5 (3R,4S)-4-((S)-1,2-Dihydroxy-ethyl)-1-(4-methoxy-phenyl)-3-(3-methyl-but-2-enyloxy)-azetidin-2-one 

Relevant academic research and scientific papers

Lewis acid-assisted ene cyclization of 2-azetidinone-tethered enals: Synthesis of enantiopure carbacepham derivatives

Diastereocontrolled Lewis acid-catalyzed preparation of enantiopure carbacepham derivatives have been developed starting from 2-azetidinone-tethered enals. The BF3.Et2O-promoted reaction of alkenylaldehydes 1 and 16 is effective as c

Rapid entry to enantiopure carbacepham derivatives via Lewis acid promoted carbonyl-ene cyclization of 2-azetidinone-tethered alkenylaldehydes

(Matrix Presented) Lewis acid promoted types I and II carbonyl-ene cyclizations of 2-azetidinone-tethered alkenylaldehydes are used for the rapid, highly diastereoselective synthesis of polyfunctionalized, enantiomerically pure carbacepham derivatives.