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(1α,4α)-1-Hydroxymethyl-4-methylcyclohexane, commonly known as isomenthol, is a terpene derivative and a member of the menthol family of compounds. It features a cyclohexane ring structure with a hydroxymethyl and methyl group attached, and is widely recognized for its cooling and soothing properties.

393-74-8

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393-74-8 Usage

Uses

Used in Fragrance and Flavoring Industries:
(1α,4α)-1-Hydroxymethyl-4-methylcyclohexane is used as a key ingredient for creating mint and menthol-flavored products, adding a refreshing and cooling sensation to various consumer goods.
Used in Pharmaceuticals:
In the pharmaceutical industry, isomenthol is utilized for its cooling and soothing effects, making it a valuable component in topical applications and other medicinal formulations.
Used in Oral Care Products:
(1α,4α)-1-Hydroxymethyl-4-methylcyclohexane is used as an active component in oral care products such as toothpaste and mouthwash, providing a fresh and cooling sensation to enhance the overall oral hygiene experience.
Used in the Synthesis of Organic Compounds:
Isomethol has potential applications in the synthesis of other organic compounds, contributing to the development of new chemical entities for various industries.
Used in Material Development:
Furthermore, isomenthol is explored for its potential use in the development of new materials, showcasing its versatility beyond traditional applications.

Check Digit Verification of cas no

The CAS Registry Mumber 393-74-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 393-74:
(5*3)+(4*9)+(3*3)+(2*7)+(1*4)=78
78 % 10 = 8
So 393-74-8 is a valid CAS Registry Number.

393-74-8Relevant academic research and scientific papers

Reconsidering glycosylations at high temperature: Precise microwave heating

Larsen, Kim,Worm-Leonhard, Kasper,Olsen, Peter,Hoel, Andreas,Jensen, Knud J.

, p. 3966 - 3970 (2007/10/03)

Current methods for glycosylation of complex alcohols, e.g. with glycosyl trichloroacetimidates, generally occur in the presence of a strong Lewis acid 'promoter', and at sub-ambient temperatures. However, the older literature reports high-temperature gly

A new, efficient glycosylation method for oligosaccharide synthesis under neutral conditions: Preparation and use of new DISAL donors

Petersen,Jensen

, p. 6268 - 6275 (2007/10/03)

Efficient, stereoselective glycosylation methods are required for the synthesis of complex oligosaccharides as tools in glycobiology. All glycosylation methods, which have found wide acceptance, rely on Lewis acid activation of glycosyl donors prior to glycosylation. Here, we present a new and efficient method for glycosylation under neutral or mildly basic conditions. Glycosides of methyl 2-hydroxy-3,5-dinitrobenzoate (DISAL) and its para regioisomer, methyl 4-hydroxy-3,5-dinitrobenzoate, were prepared by nucleophilic aromatic substitution. In a first demonstration of their potential as glycosyl donors, stereospecific glycosylation of methanol was achieved. In the glycosylation of more hindered alcohols, the β-donor proved more reactive, and α-glucosides were predominantly formed. Glycosylation of protected monosaccharides, with free 6-0H or 3-OH, proceeded smoothly in 1-methyl-2-pyrrolidinone (NMP) at 40-60 °C in the absence of Lewis acids and bases in good to excellent yields. Glycosylation of 3-OH gave the α-linked disaccharide only.

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