393536-26-0

Basic information

• Product Name: (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)pentyl)amide
• CAS NO: 393536-26-0
• Molecular Weight: 311.489
• Mol File: 393536-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)pentyl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)pentyl)amide(393536-26-0)
• EPA Substance Registry System: (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)pentyl)amide(393536-26-0)

Safety Data

• Hazardous Substances Data: 393536-26-0(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 393536-17-9 (R)-N-[(1E)-2-(benzyloxy)ethylidene]-2-methylpropane-2-sulfinamide 
• 60656-87-3 benzyloxyacetoaldehyde 

Downstream Products

• 80696-28-2 (2R)-2-amino-2-butyl-1-ethanol 

Relevant articles and documents

Asymmetric synthesis of protected 1,2-amino alcohols using tert-butanesulfinyl aldimines and ketimines

tert-Butanesulfinyl aldimines and ketimines bearing an α-benzyloxy or α-silyloxy substituent serve as precursors in the synthesis of protected 1,2-amino alcohols in high yields and diastereoselectivities. General protocols are described for the addition of unbranched alkyl, branched alkyl, and aryl organometallic reagents to N-sulfinyl aldimines 1 and 2 and ketimines 5 and 6. Furthermore, the selective N- or O-deprotection of sulfinamide products 3, 4, 7, and 8 is described, enabling further synthetic transformations of the reaction products.