393536-67-9

Basic information

• Product Name: (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine
• Synonyms: (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine
• CAS NO: 393536-67-9
• Molecular Weight: 207.316
• Mol File: 393536-67-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine(393536-67-9)
• EPA Substance Registry System: (R)-1-(benzyloxymethyl)-2,2-dimethylpropylamine(393536-67-9)

Safety Data

• Hazardous Substances Data: 393536-67-9(Hazardous Substances Data)

Upstream product

• 393536-17-9 (R)-N-[(1E)-2-(benzyloxy)ethylidene]-2-methylpropane-2-sulfinamide 
• 60656-87-3 benzyloxyacetoaldehyde 
• 393536-30-6 (R_S,1R)-2-methylpropane-2-sulfinic acid (1-(benzyloxymethyl)-2,2-dimethylpropyl)amide 

Downstream Products

• 3907-02-6 (2R)-2-amino-3,3-dimethylbutan-1-ol 
• 1612163-80-0 (R)-O-benzoyl-N-(1-(benzyloxy)-3,3-dimethylbutan-2-yl)-hydroxylamine 
• 1612163-49-1 (S)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromophenyl)-N-(tert-butyl)-N-methylacetamide 
• 1612163-55-9 (R)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromophenyl)-N-(tert-butyl)-N-methylacetamide 
• 1612163-47-9 (S)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromo-phenyl)-N,N-diisopropylacetamide 
• 1612163-53-7 (R)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromo-phenyl)-N,N-diisopropylacetamide 
• 1612163-45-7 (S)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromo-phenyl)-N,N-dimethylacetamide 
• 1612163-51-5 (R)-2-(((R)-1-(benzyloxy)-3,3-dimethylbutan-2-yl)(hydroxy)-amino)-2-(4-bromo-phenyl)-N,N-dimethylacetamide 
• 1612163-84-4 (R,Z)-N-(1-(benzyloxy)-3,3-dimethylbutan-2-yl)-1-(4-bromophenyl)methanimine oxide 
• 1612163-82-2 (R)-N-(1-(benzyloxy)-3,3-dimethylbutan-2-yl)hydroxylamine 

Relevant articles and documents

Asymmetric synthesis of protected 1,2-amino alcohols using tert-butanesulfinyl aldimines and ketimines

tert-Butanesulfinyl aldimines and ketimines bearing an α-benzyloxy or α-silyloxy substituent serve as precursors in the synthesis of protected 1,2-amino alcohols in high yields and diastereoselectivities. General protocols are described for the addition of unbranched alkyl, branched alkyl, and aryl organometallic reagents to N-sulfinyl aldimines 1 and 2 and ketimines 5 and 6. Furthermore, the selective N- or O-deprotection of sulfinamide products 3, 4, 7, and 8 is described, enabling further synthetic transformations of the reaction products.