39368-46-2

Upstream product

• 147779-14-4 3-Benzyl-4-(1-methyl-1H-imidazol-4-yl)-2-oxo-3-phenylselanyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 147779-02-0 (2E)-N-allyl-N-benzyl-3-phenylacrylamide 
• 147779-15-5 4-(1-Methyl-1H-imidazol-4-yl)-2-oxo-3-[1-phenyl-meth-(E)-ylidene]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 85651-90-7 noranantine 
• 74-88-4 methyl iodide 
• 85198-97-6 1-Acetyl-3-(hydroxy-phenyl-methyl)-4-(1-methyl-1H-imidazol-4-yl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Radical cyclization in heterocycle synthesis. II. Total synthesis of (±)-anantine and (±)-isoanantine

(+)-Anantine, (±)-isoanantine and related compounds were synthesized via two key reactions, sulfanyl radical addition-cyclization and stereoselective construction of the E-benzylidene moiety.

Total synthesis of (±)-anantine and [±]-isoanantine via thiyl radical addition-cyclization reaction

A new stereoselective route to isonantine (1) and anantine (2) has been developed by the combination of three key steps: thiyl radical addition-cyclization of dienylamide, construction of the substituted imidazole, and stereoselective construction of the

ALCALOIDES IMIDAZOLIQUES-VI. ALCALOIDES DU CYNOMETRA LUJAE ISOLEMENT,STRUCTURES, SYNTHESE

Eight imidazole alcaloids were isolated from Cynometra lujae: anantine, noranantine, cynometrine, isoanantine, isocynometrine, isocynodine, hydroxyanantine and cynolujine.The syntheses of isoanantine and isocynometrine were achieved starting from 1-methyl-5-methoxycarbonyl imidazole and those of anantine and cynometrine starting from 1-methyl-4-methoxycarbonyl imidazole.