393845-24-4 Usage
Uses
Used in Pharmaceutical Industry:
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine is used as a potential drug candidate for its unique structural features. Its complex molecular composition allows for the possibility of targeting specific biological pathways or receptors, which could be beneficial in the development of new medications for various diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine serves as a subject of study for its synthesis and biological activities. Researchers are interested in understanding the compound's properties and how they can be harnessed for therapeutic purposes, potentially leading to valuable insights in drug discovery and development.
Used in Drug Development:
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine is also used in drug development as a starting point for designing new pharmaceuticals. Its structural features can be modified or optimized to enhance its therapeutic potential, making it a versatile building block for creating novel drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 393845-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,3,8,4 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 393845-24:
(8*3)+(7*9)+(6*3)+(5*8)+(4*4)+(3*5)+(2*2)+(1*4)=184
184 % 10 = 4
So 393845-24-4 is a valid CAS Registry Number.
393845-24-4Relevant academic research and scientific papers
Microwave-assisted protocols for the expedited synthesis of pyrazolo[1,5-a] and [3,4-d]pyrimidines
Daniels, R. Nathan,Kim, Kwangho,Lebois, Evan P.,Muchalski, Hubert,Hughes, Mary,Lindsley, Craig W.
, p. 305 - 310 (2008/09/17)
General, high-yielding MAOS protocols for the expedited synthesis of functionalized pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-b]pyrimidines, as well as their pyrazole precursors, are described amenable to an iterative analogue library synthesis strategy for lead optimization.
Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators
Niswender, Colleen M.,Lebois, Evan P.,Luo, Qingwei,Kim, Kwangho,Muchalski, Hubert,Yin, Huiyong,Conn, P. Jeffrey,Lindsley, Craig W.
experimental part, p. 5626 - 5630 (2009/07/18)
This letter describes the synthesis and SAR, developed through an iterative analogue library approach, of an mGluR4 positive allosteric modulator lead based on a pyrazolo[3,4-d]pyrimidine scaffold. Despite tremendous therapeutic potential, Compound 7, VU0080421, and related congeners represent only a handful of mGluR4 positive allosteric modulators ever described.
