394661-77-9Relevant articles and documents
Hydroporphyrins as tumour photosensitizers: Synthesis and photophysical studies of 2,3-dihydro-5,15-di(3,5-dihydroxyphenyl) porphyrin
Ferrand, Yann,Bourre, Ludovic,Simonneaux, G.erard,Thibaut, Sonia,Odobel, Fabrice,Lajat,Patrice, Thierry
, p. 833 - 835 (2003)
The synthesis and characterization of 2,3-dihydro-5,15-di(3,5-dihydroxyphenyl) porphyrin is reported. The phototoxicity on C6 cell lines and the pharmacokinetics are also reported as preliminary results showing a very high tumor to skin ratio and short retention time in tissues, and thus promising activity in photodynamic therapy.