394738-18-2Relevant academic research and scientific papers
Application of the AAA reaction to the synthesis of the furanoside of C-2-epi-hygromycin A: A total synthesis of C-2-epi-hygromycin A
Trost, Barry M.,Dudash Jr., Joseph,Dirat, Olivier
, p. 259 - 268 (2007/10/03)
A strategy for stereocontrolled syntheses of furanoside type of natural products is developed for a glycosyl aryl ether. This strategy resolves the issue of low diastereoselectivity typical of normal glycosidation methods for furanosides. All the stereoch
An asymmetric synthesis of c-2-epi-hygromycin a
Trost, Barry M.,Dirat, Olivier,Dudash Jr., Joseph,Hembre, Erik J.
, p. 3658 - 3660 (2007/10/03)
The power of Pd-catalyzed asymmetric allylic alkylation (AAA) reactions is clearly demonstrated by the efficient synthesis of the complex title compound 1, an analogue of hygromycin A. The modular nature of the synthetic route is ideally suited to provide
