394738-99-9

Basic information

• Product Name: 2H-Pyran, tetrahydro-2-[[4-(1-methylethyl)phenyl]methoxy]-
• CAS NO: 394738-99-9
• Molecular Formula: C15H22O2
• Molecular Weight: 234.338
• Mol File: 394738-99-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Pyran, tetrahydro-2-[[4-(1-methylethyl)phenyl]methoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran, tetrahydro-2-[[4-(1-methylethyl)phenyl]methoxy]-(394738-99-9)
• EPA Substance Registry System: 2H-Pyran, tetrahydro-2-[[4-(1-methylethyl)phenyl]methoxy]-(394738-99-9)

Safety Data

• Hazardous Substances Data: 394738-99-9(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 536-60-7 cuminol 

Downstream Products

• 122-03-2 (4-isopropylbenzaldehyde) 
• 99-87-6 4-methylisopropylbenzene 

Relevant articles and documents

Efficient and convenient procedure for protection of hydroxyl groups to the THP, THF and TMS ethers and oxidation of these ethers to their aldehydes or ketones in [BPy]FeCl4 as a low cost room temperature ionic liquid

Alcohols were converted to the corresponding THP, THF or TMS ethers in high to excellent yields in 1-n-butylpyridinium chloroferrate media as a stable and low cost room temperature ionic liquid. In addition, oxidation of these ethers to their aldehydes or ketones without any overoxidation reactions in this ionic liquid was also performed.

Lithium triflate (LiOTf) catalyzed efficient and chemoselective tetrahydropyranylation of alcohols and phenols under mild and neutral reaction conditions

Different types of alcohols and phenols were effectively converted to the corresponding THP ethers in the presence of DHP and a catalytic amount of lithium trifluoromethanesulfonate (LiOTf) in refluxing 1,2-dichloroethane under essentially neutral reaction conditions. The method also shows good chemoselectivity for mono-tetrahydropyranylation of symmetrical diols.