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Hexabutylthiophosphoramide, also known as HBT, is an organophosphorus compound characterized by its clear, colorless liquid form and a strong odor. It serves as a crucial reagent in organic synthesis, particularly recognized for its role as a phosphitylating agent in various organic chemistry reactions. HBT's utility extends to the creation of phosphoramidite building blocks, which are integral to the synthesis of oligonucleotides. Furthermore, its application in the preparation of phosphoramidite reagents for automated DNA and RNA synthesis highlights its significance in molecular biology. HBT also finds use as a coupling reagent in the formation of peptide and protein conjugates, underscoring its versatility in chemical research and development.

3949-47-1

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3949-47-1 Usage

Uses

Used in Organic Synthesis:
HEXABUTYLTHIOPHOSPHORAMIDE is used as a reagent for its phosphitylating properties, facilitating a range of organic chemistry reactions that require the formation of phosphorus-containing compounds.
Used in Oligonucleotide Synthesis:
HEXABUTYLTHIOPHOSPHORAMIDE is used as a phosphitylating agent for the synthesis of phosphoramidite building blocks, which are essential in the construction of oligonucleotides, playing a pivotal role in molecular biology research and applications.
Used in Automated DNA and RNA Synthesis:
HEXABUTYLTHIOPHOSPHORAMIDE is utilized in the preparation of phosphoramidite reagents that are crucial for the automated processes involved in DNA and RNA synthesis, enabling efficient and accurate production of nucleic acid sequences.
Used in Pharmaceutical and Bioconjugate Production:
HEXABUTYLTHIOPHOSPHORAMIDE is used as a coupling reagent in the production of peptide and protein conjugates, which is vital for the development of new drugs and bioconjugates with specific targeting and therapeutic properties.
Used in Research and Development:
HEXABUTYLTHIOPHOSPHORAMIDE is employed across various industries for research and development purposes, given its reactivity and high potential for reaction, making it a valuable tool in advancing scientific knowledge and creating innovative products. Due to its sensitivity to moisture, HEXABUTYLTHIOPHOSPHORAMIDE necessitates careful handling and storage to maintain its reactivity and effectiveness in these applications.

Check Digit Verification of cas no

The CAS Registry Mumber 3949-47-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,4 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3949-47:
(6*3)+(5*9)+(4*4)+(3*9)+(2*4)+(1*7)=121
121 % 10 = 1
So 3949-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H54N3PS/c1-7-13-19-25(20-14-8-2)28(29,26(21-15-9-3)22-16-10-4)27(23-17-11-5)24-18-12-6/h7-24H2,1-6H3

3949-47-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name N-bis(dibutylamino)phosphinothioyl-N-butylbutan-1-amine

1.2 Other means of identification

Product number -
Other names phosphinotris(dibutylamino)-1-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3949-47-1 SDS

3949-47-1Downstream Products

3949-47-1Relevant academic research and scientific papers

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