395099-79-3
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Basic information
- Product Name: 1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(tetrahydro-2H-pyran-2-yl)-
- Synonyms:
- CAS NO:395099-79-3
- Molecular Formula: C17H18N4O
- Molecular Weight:
- EINECS: N/A
- Product Categories: N/A
- Mol File: 395099-79-3.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(tetrahydro-2H-pyran-2-yl)-(CAS DataBase Reference)
- NIST Chemistry Reference: 1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(tetrahydro-2H-pyran-2-yl)-(395099-79-3)
- EPA Substance Registry System: 1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(tetrahydro-2H-pyran-2-yl)-(395099-79-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 395099-79-3(Hazardous Substances Data)
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Molecular structure
The compound has an indazole ring, a pyridine ring, and a tetrahydro-2H-pyran ring.Anti-cancer properties
TAK-243 has potential anti-cancer properties due to its ability to inhibit the enzyme UBE1.Inhibition of UBE1
TAK-243 is a small molecule inhibitor of the enzyme ubiquitin-activating enzyme (UBE1).Role of UBE1
UBE1 is involved in the initial step of the ubiquitin-proteasome pathway, which regulates the degradation of proteins involved in cell cycle control, signal transduction, and DNA repair.Effect on cancer cells
Inhibition of UBE1 by TAK-243 leads to the accumulation of polyubiquitinated proteins and induction of apoptosis in cancer cells.Potential treatment
TAK-243 is a potential candidate for the treatment of various types of cancer.Ongoing research
Further research is being conducted to explore the therapeutic potential of this chemical compound.Check Digit Verification of cas no
The CAS Registry Mumber 395099-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,5,0,9 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.Calculate Digit Verification of CAS Registry Number 395099-79:
(8*3)+(7*9)+(6*5)+(5*0)+(4*9)+(3*9)+(2*7)+(1*9)=203
203 % 10 = 3
So 395099-79-3 is a valid CAS Registry Number.
395099-79-3Upstream product
395099-79-3Downstream Products
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1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(tetrahydro-2H-pyran-2-yl)-
