39516-27-3

Basic information

• Product Name: 1,10-DODECANEDIOL
• Synonyms: (10S)-dodecane-1,10-diol;1,10-DODECANEDIOL
• CAS NO: 39516-27-3
• Molecular Formula: C12H26O2
• Molecular Weight: 202.33364
• Mol File: 39516-27-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 323.6°C at 760 mmHg
• Flash Point: 146°C
• Appearance: /
• Density: 0.911g/cm³
• Vapor Pressure: 2.04E-05mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 1,10-DODECANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,10-DODECANEDIOL(39516-27-3)
• EPA Substance Registry System: 1,10-DODECANEDIOL(39516-27-3)

Safety Data

• Hazardous Substances Data: 39516-27-3(Hazardous Substances Data)

Usage

General Description

1,10-Dodecanediol is a chemical compound with the molecular formula C12H26O2. It is a diol, meaning it contains two hydroxyl groups (-OH) attached to carbon atoms. 1,10-Dodecanediol is commonly used as a precursor in the production of polyesters, polyurethanes, and other polymers. It is also used as a lubricant, plasticizer, and surfactant in various industrial applications. Due to its ability to form hydrogen bonds, 1,10-Dodecanediol is also used in the formulation of personal care products such as lotions, creams, and hair care products. Additionally, it has antimicrobial properties and can be used as a preservative in cosmetics and pharmaceuticals.

InChI:InChI=1/C12H26O2/c1-2-12(14)10-8-6-4-3-5-7-9-11-13/h12-14H,2-11H2,1H3/t12-/m0/s1

Upstream product

• 412017-38-0 10-oxo-dodecanoic acid ethyl ester 
• 112-53-8 1-dodecyl alcohol 
• 10467-10-4 ethylmagnesium iodide 

Relevant articles and documents

CYP505E3: A Novel Self-Sufficient ω-7 In-Chain Hydroxylase

The self-sufficient cytochrome P450 monooxygenase CYP505E3 from Aspergillus terreus catalyzes the regioselective in-chain hydroxylation of alkanes, fatty alcohols, and fatty acids at the ω-7 position. It is the first reported P450 to give regioselective in-chain ω-7 hydroxylation of C10–C16 n-alkanes, thereby enabling the one step biocatalytic synthesis of rare alcohols such as 5-dodecanol and 7-tetradecanol. It shows more than 70 percent regioselectivity for the eighth carbon from one methyl terminus, and displays remarkably high activity towards decane (TTN≈8000) and dodecane (TTN≈2000). CYP505E3 can be used to synthesize the high-value flavour compound δ-dodecalactone via two routes: 1) conversion of dodecanoic acid into 5-hydroxydodecanoic acid (24 percent regioselectivity), which at low pH lactonises to δ-dodecalactone, and 2) conversion of 1-dodecanol into 1,5-dodecanediol (55 percent regioselectivity), which can be converted into δ-dodecalactone by horse liver alcohol dehydrogenase.