3953-65-9

Basic information

• Product Name: Demethyl Chlorpromazine Hydrochloride
• Synonyms: Demethyl Chlorpromazine Hydrochloride;2-Chloro-10-(3-MethylaMinopropyl)phenothiazine Hydrochloride;2-Chloro-N-Methyl-10H-phenothiazine-10-propanaMine Hydrochloride;DesMethylchlorproMazine Hydrochloride;Mono-N-deMethylchloroproMazine Hydrochloride;Mono-N-deMethylchlorproMazine Hydrochloride;SKF 4514A;Chlorpromazine EP impurity D
• CAS NO: 3953-65-9
• Molecular Formula: C₁₆H₁₇ClN₂S*ClH
• Molecular Weight: 341.29852
• Product Categories: Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 3953-65-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 178-180°C
• Boiling Point: 458.2°C at 760 mmHg
• Flash Point: 230.9°C
• Appearance: /
• Vapor Pressure: 1.4E-08mmHg at 25°C
• Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
• CAS DataBase Reference: Demethyl Chlorpromazine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Demethyl Chlorpromazine Hydrochloride(3953-65-9)
• EPA Substance Registry System: Demethyl Chlorpromazine Hydrochloride(3953-65-9)

Safety Data

• Hazardous Substances Data: 3953-65-9(Hazardous Substances Data)

Usage

Chemical Properties

White to Off-White Solid

Uses

A metabolite of Chlorpromazine (C424750).

InChI:InChI=1/C16H17ClN2S.ClH/c1-18-9-4-10-19-13-5-2-3-6-15(13)20-16-8-7-12(17)11-14(16)19;/h2-3,5-8,11,18H,4,9-10H2,1H3;1H

Upstream product

• 50-53-3 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine 
• 92-39-7 2-chlorophenothiazine 

Downstream Products

• 50-53-3 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine 
• 22724-15-8 N-[3-(2-chloro-phenothiazin-10-yl)-propyl]-N-methyl-toluene-4-sulfonamide 

Relevant articles and documents

Chlorpromazine derivative, preparation method thereof and chlorpromazine detection reagent

The invention discloses a chlorpromazine derivative for detecting the content of chlorpromazine in a human body biological sample and a preparation method of the chlorpromazine derivative. A series ofanti-chlorpromazine specific antibodies developed by utilizing the novel chlorpromazine derivative disclosed by the invention can be used for preparing various chlorpromazine immunological detectionreagents with high sensitivity, strong specificity and good detection effect. The invention also provides preparation methods and corresponding using methods of three chlorpromazine immunoassay reagents. The three chlorpromazine immunoassay methods provided by the invention are convenient to operate, rapid in detection, accurate in result, high in sensitivity and strong in specificity, and can beused for quantitatively detecting of the content of chlorpromazine in human blood samples. The defects of complex operation, low automation degree and the like of a chlorpromazine detection method inthe prior art are avoided, and clinical individualized reasonable medication can be effectively guided.