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4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine is a chemical compound with the molecular formula C9H6F3N3S. It is a heterocyclic molecule that features a pyrimidine ring, which is a six-membered aromatic ring containing two nitrogen atoms. The compound is characterized by the presence of a thiophene group (a five-membered ring with one sulfur atom) at the 4-position and a trifluoromethyl group (-CF3) at the 6-position. The 2-amine functional group, which contains an amino group (-NH2), is attached to the pyrimidine ring. 4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine is of interest in medicinal chemistry and drug discovery due to its potential as a building block for the development of new therapeutic agents, particularly in the area of antiviral and anticancer research. Its specific properties and reactivity make it a valuable candidate for further exploration in the synthesis of more complex molecules with potential biological activity.

396-63-4

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396-63-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 396-63-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 396-63:
(5*3)+(4*9)+(3*6)+(2*6)+(1*3)=84
84 % 10 = 4
So 396-63-4 is a valid CAS Registry Number.

396-63-4Downstream Products

396-63-4Relevant academic research and scientific papers

Improved Synthesis of Fluoroalkyl and Fluoroaryl Substituted 2-Aminopyrimidines

Kucerovy, Andrew,Mattner, Paul G.,Hathaway, Joel S.,Repic, Oljan

, p. 913 - 917 (2007/10/02)

Fluoroalkyl and fluoroaryl substituted 2-aminopyrimidines have been prepared in good yields by the cyclization of guanidine salts with fluorine substituted β-diketones in sodium isopropoxide/isopropanol at reflux.

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