39624-20-9Relevant academic research and scientific papers
N,N'-bis-[(β-hydroxy-β-phenyl)-ethyl]-polymethylenediamines and salts thereof
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, (2008/06/13)
Compounds of the formula STR1 WHEREIN R1 is hydrogen or methyl, m is 0 or an integer from 1 to 8, inclusive, and Ar is STR2 WHERE R is hydrogen or acyl, and R2 is hydrogen or --OR, as defined above, STR3 WHERE R has the meanings defined above, and R3 is hydroxy-lower alkyl, --NH--CO--R4, --NH--SO2 --R5, --CH2 --NH--CO--R4, --CH2 --NH--SO2 --R5 or --CH2 --NH--CO--NH--R4, where R4 is hydrogen or lower alkyl, and R5 is lower alkyl or di-lower alkyl-amino, STR4 WHERE R6 is hydrogen, amino or hydroxyl, X is chlorine or bromine, and Y is hydrogen, chlorine or bromine or STR5 WHERE R has the meanings defined above, and A is a saturated or unsaturated 5- to 6-membered ring, And their non-toxic, pharmacologically acceptable acid addition salts; the compounds as well as their salts are useful as bronchospasmolytics, uterine spasmolytics, antipruritics and antiallergics.
