39632-82-1

Basic information

• Product Name: 3,4-diethyl 2-methyl-6-phenylpyridine-3,4-dicarboxylate
• Synonyms: 3,4-diethyl 2-methyl-6-phenylpyridine-3,4-dicarboxylate
• CAS NO: 39632-82-1
• Molecular Weight: 313.353
• Mol File: 39632-82-1.mol

Chemical Properties

• CAS DataBase Reference: 3,4-diethyl 2-methyl-6-phenylpyridine-3,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diethyl 2-methyl-6-phenylpyridine-3,4-dicarboxylate(39632-82-1)
• EPA Substance Registry System: 3,4-diethyl 2-methyl-6-phenylpyridine-3,4-dicarboxylate(39632-82-1)

Safety Data

• Hazardous Substances Data: 39632-82-1(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 14369-81-4 ethyl 2,3-butadienoate 
• 57957-24-1 N-(1-phenylvinyl)acetamide 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 

Downstream Products

• 173211-58-0 2-methyl-6-phenyl-pyridine-3,4-dicarboxylic acid 

Relevant articles and documents

Organocatalytic synthesis of highly functionalized pyridines at room temperature

Amines by all means: A unique aza-Rauhut-Currier/cyclization/desulfonation cascade reaction between allenoates and N-sulfonyl-1-aza-1,3-dienes, catalyzed by the readily available diamine TMEDA, has been developed. This strategy provides facile access to a broad range of valuable highly functionalized pyridines in good yields under very mild reaction conditions. Copyright

Copper-Catalyzed N-O Cleavage of α,β-Unsaturated Ketoxime Acetates toward Structurally Diverse Pyridines

The copper-catalyzed [4 + 2] annulation of α,β-unsaturated ketoxime acetates with 1,3-dicarbonyl compounds for the synthesis of three classes of structurally diverse pyridines has been developed. This method employs 1,3-dicarbonyl compounds as C2 synthons and enables the synthesis of multifunctionalized pyridines with diverse electron-withdrawing groups in moderate to good yields. The mechanistic investigation suggests that the reactions proceed through an ionic pathway.

Coupling of enamides with alkynes or arynes for synthesis of substituted pyridines and isoquinolines via amide activation

A novel and general procedure for Cu-catalyzed coupling of enamides with alkynes to synthesize substituted pyridines was developed. The chemistry was allowed to extend to the synthesis of substituted isoquinolines by coupling of enamides with arynes under transition-metal-free conditions.