39640-51-2

Basic information

• Product Name: ETHYL 6-METHYL-2-PYRIDINECARBOXYLATE 9&
• Synonyms: ETHYL 6-METHYL-2-PYRIDINECARBOXYLATE 9&;6-Methyl-ALPHA-picolinic acid ethyl ester;6-methyl-pyridine-2-carboxylic acid ethyl ester;6-Methyl-pyridine-2-carboxylic acid ethyl ester, Ethyl 6-methyl-2-pyridinecarboxylate;Ethyl 6-methylpyridine-2-carboxylate;2-Pyridinecarboxylic acid, 6-Methyl-, ethyl ester;ethyl 6-methylpicolinate
• CAS NO: 39640-51-2
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Product Categories: Heterocyclic Compounds
• Mol File: 39640-51-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 122-126 °C/10 mmHg(lit.)
• Flash Point: 110.3oC
• Appearance: /
• Density: 1.083 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0135mmHg at 25°C
• Refractive Index: n20/D 1.5090(lit.)
• PKA: 2.06±0.10(Predicted)
• CAS DataBase Reference: ETHYL 6-METHYL-2-PYRIDINECARBOXYLATE 9&(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 6-METHYL-2-PYRIDINECARBOXYLATE 9&(39640-51-2)
• EPA Substance Registry System: ETHYL 6-METHYL-2-PYRIDINECARBOXYLATE 9&(39640-51-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 39640-51-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO2/c1-3-12-9(11)8-6-4-5-7(2)10-8/h4-6H,3H2,1-2H3

Upstream product

• 934-60-1 6-methyl-2-pyridinecarboxylic acid 
• 64-17-5 ethanol 
• 1197-10-0 6-(hydroxymethyl)pyridine-2-carboxylic acid 
• 108-48-5 2,6-dimethylpyridine 

Downstream Products

• 109810-30-2 2-methyl-6-(diphenylhydroxymethyl)pyridine 
• 100869-96-3 N-benzyl-6-methylpicolinamide 
• 98547-86-5 6-methyl-2-picolinic acid hydrazide 
• 115453-98-0 Ethyl 6-(4'-nitrostyryl)picolinate 
• 115153-56-5 methyl (E)-6-styrylpicolinate 
• 115153-57-6 6-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-pyridine-2-carboxylic acid ethyl ester 
• 115153-58-7 6-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-pyridine-2-carboxylic acid ethyl ester 
• 101938-10-7 2-methyl-6-(1-(phenylmethylamino)methyl)pyridine 
• 100867-62-7 6-methyl-pyridine-2-carboxylic acid benzylidenehydrazide 
• 101281-48-5 6-methyl-pyridine-2-carboxylic acid-(4-acetylamino-benzylidenehydrazide) 
• 109502-67-2 2,3-dimethoxy-6-[(6-methyl-pyridine-2-carbonylhydrazono)-methyl]-benzoic acid 
• 868395-53-3 3-(6-methylpyridin-2-yl)-3-oxopropionitrile 
• 879486-39-2 2-(3-bromo-phenyl)-1-(6-methyl-pyridin-2-yl)ethanone 
• 607737-87-1 4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline 

Relevant articles and documents

BENZYLAMIDE DERIVATIVES AS INHIBITORS OF TRANSFORMING GROWTH FACTOR-BETA RECEPTOR I/ALK5

The present invention relates to novel benzylamide derivatives of formula (I) to processes for the preparation of said compounds; to pharmaceutical compositions comprising said compounds and to said compounds for use in the treatment of pathological conditions or diseases that can improve by inhibition of transforming growth factor-β receptor I (TGFβRI)/ALK5, such as diseases and disorders associated to fibrotic conditions of gastrointestinal system, skin and eyes, to methods for the treatment and/or prevention of said diseases or pathological conditions and to combinations comprising said compounds and further comprising therapeutically effective amounts of other therapeutic agents useful for the treatment of said diseases or pathological conditions.

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF CANCERS, INCLUDING HEPATOCELLULAR CARCINOMA, AND AS INHIBITORS OF HEPATITIS VIRUS REPLICATION

Pharmaceutical compositions of the invention are presented which comprise substiuted aminothiazoles derivatives. The substiuted aminothiazoles derivatives have a disease-modifying action in the treatment of diseases associated with unregulated cell growth. Such diseases include cancers such as hepatocellular carcinoma, and viral infections from a hepatitis virus.

THERAMUTEIN MODULATORS

This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.