39648-48-1 Usage
Uses
Used in Pharmaceutical Industry:
(+)-2-(2,2-dicyclohexylethyl)piperidine is used as a chiral building block for the synthesis of enantiomerically pure compounds. Its unique structure and reactivity contribute to the development of new drugs with improved selectivity and efficacy.
Used in Asymmetric Synthesis:
(+)-2-(2,2-dicyclohexylethyl)piperidine is used as a chiral auxiliary in asymmetric synthesis to enhance the selectivity of certain reactions. Its bulky substituent provides steric hindrance, which aids in the formation of specific enantiomers and improves the overall yield of the desired product.
Used in Organic Chemistry Research:
(+)-2-(2,2-dicyclohexylethyl)piperidine is used as a valuable tool by organic chemists for the development of new drugs and materials. Its high stereoselectivity and unique reactivity make it an essential component in the exploration of novel synthetic pathways and the creation of innovative chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 39648-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,6,4 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39648-48:
(7*3)+(6*9)+(5*6)+(4*4)+(3*8)+(2*4)+(1*8)=161
161 % 10 = 1
So 39648-48-1 is a valid CAS Registry Number.
39648-48-1Relevant academic research and scientific papers
Influence of [2H]-labelled acetic acid as solvent in the synthesis of [2H]-labelled perhexiline
Schou, Soren Christian
experimental part, p. 31 - 35 (2010/04/24)
Preparation of deuterium-labelled perhexiline from an unsaturated analogue was performed via reduction with deuterium gas and PtO2 in acetic acid. Low incorporation was observed when using acetic acid as solvent (most abundant mass peak was MD0+ ), but when changing the solvent to deuterium-labelled acetic acid, e.g. acetic acid-OD or acetic acid-d4, a higher incorporation was observed (most abundant mass peak was MD8+). Using hydrogen gas instead of deuterium gas withdeuterium-labelled acetic acid, high levels of deuterium incorporation were observed (most abundant mass peak was MD5+). An attempt to reduce a precursor with a fully deuterated pyridine to obtain perhexiline with a higher content of deuterium failed. Copyright
Process for preparing 2-(2,2-dicyclohexylethyl)piperidine
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, (2008/06/13)
2-(2,2-Dicyclohexylethyl)piperidine is prepared via the catalytic hydrogenation of 2-(2,2-diphenylethenyl)pyridine in a single step. High yields are obtained using an anhydrous Raney nickel catalyst.
