396650-48-9

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 396650-42-3 5-[2-deoxy-β-D-erythro-pentofuranosyl]-2-{[(dimethylamino)methylidene]amino}-3,5-dihydro-3-[(pivaloyloxy)methyl]-4H-pyrrolo[3,2-d]pyrimidin-4-one 
• 151587-58-5 2-<<(N,N-Dimethylamino)methylene>amino>-4(3H)-oxo-3-<(pivaloyloxy)methyl>-5H-pyrrolo<3,2-d>pyrimidine 
• 396650-34-3 5-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-2-{[(dimethylamino)methylidene]amino}-3,5-dihydro-3-[(pivaloyloxy)methyl]-4H-pyrrolo[3,2-d]pyrimidin-4-one 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 

Relevant academic research and scientific papers

Synthesis and base pairing properties of 9-deazapurine N7-nucleosides in oligonucleotide duplexes and triplexes

The 9-deazaguanine N7-2′-deoxyribofuranoside (3) as well as the bromo and iodo derivatives 4a,b were synthesized and incorporated in oligonculeotide duplexes and triplexes. Their base pairing properties were investigated and compared with those

pH-independent recognition of the dG·dC base pair in triplex DNA: 9-Deazaguanine N7-(2′-deoxyribonucleoside) and halogenated derivatives replacing protonated dC

Triplex-forming oligonucleotides (TFOs) containing 9-deazaguanine N 7-(2′-deoxyribonucleoside) 1a and halogenated derivatives 1b,c were synthesized employing solid-phase oligonucleotide synthesis. For that purpose, the phosphoramidite building