396732-00-6Relevant articles and documents
Decarboxylative C–C and C–N Bond Formation by Ligand-Accelerated Iron Photocatalysis
Feng, Guangshou,Wang, Xiaofei,Jin, Jian
, p. 6728 - 6732 (2019)
The photoexcited state lifetimes of iron complexes are typically much shorter than those of iridium and ruthenium complexes. For that reason, iron complexes find less application in photochemical organic synthesis. Through iron photocatalysis, a mild and
Alkylation Reactions of Azodicarboxylate Esters with 4-Alkyl-1,4-Dihydropyridines under Catalyst-Free Conditions
Nakajima, Kazunari,Zhang, Yulin,Nishibayashi, Yoshiaki
supporting information, p. 4642 - 4645 (2019/06/17)
Introduction of alkyl groups on azodicarboxylate esters is an important method to prepare alkyl amine derivatives. Herein, we report reactions of 4-alkyl-1,4-dihydropyridines as alkylation reagents with di-tert-butyl azodicarboxylate to prepare alkyl amin
Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis
Yatham, Veera Reddy,Bellotti, Peter,K?nig, Burkhard
supporting information, p. 3489 - 3492 (2019/03/26)
We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.
Synthesis of N-propargylphenelzine and analogues as neuroprotective agents
Ling, Lei,Urichuk, Liana J.,Sloley,Coutts, Ronald T.,Baker, Glen B.,Shan, Jacqueline J.,Pang, Peter K.T.
, p. 2715 - 2717 (2007/10/03)
A series of N1- and N2-propargylphenelzine derivatives and analogues (1-7) was synthesized. In addition to their activity as monoamine oxidase inhibitors, two of the compounds, N1- and N2-propargylphenelzines (3 and 6), were found to be potent at preventing DSP-4-induced noradrenaline (NA) depletion in mouse hippocampus, suggesting that they have neuroprotective properties.