3970-41-0

Basic information

• Product Name: 2-CHLORO-3-NITROANILINE
• Synonyms: Aniline, 2-chloro-3-nitro-
• CAS NO: 3970-41-0
• Molecular Formula: C₆H₅ClN₂O₂
• Molecular Weight: 172.57
• Mol File: 3970-41-0.mol

Chemical Properties

• Melting Point: 95-96 °C
• Boiling Point: 318.2±22.0 °C(Predicted)
• Appearance: /
• Density: 1.494±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 0.51±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-3-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-NITROANILINE(3970-41-0)
• EPA Substance Registry System: 2-CHLORO-3-NITROANILINE(3970-41-0)

Safety Data

• Hazardous Substances Data: 3970-41-0(Hazardous Substances Data)

Usage

Uses

Used in Textile Industry:
2-Chloro-3-nitroaniline is used as an intermediate in the production of dyes and pigments for textiles, providing a wide range of colors and enhancing the durability and vibrancy of fabrics.
Used in Plastics Industry:
In the plastics industry, 2-CHLORO-3-NITROANILINE is utilized as a precursor for the synthesis of colorants, contributing to the aesthetic appeal and customization of plastic products.
Used in Chemical Synthesis:
2-Chloro-3-nitroaniline serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals, due to its reactive functional groups.
Safety Precautions:
It is crucial to handle 2-CHLORO-3-NITROANILINE with care, as it can be harmful if ingested, inhaled, or absorbed through the skin. Proper safety measures, including the use of personal protective equipment and adherence to handling protocols, should be implemented to minimize potential health risks.

Upstream product

• 606-21-3 1-chloro-2,6-dinitrobenzene 
• 606-22-4 2,6-dinitroaniline 
• 99-09-2 3-nitro-aniline 

Downstream Products

• 683238-59-7 2-chloro-1-iodo-3-nitro-benzene 
• 408314-59-0 2-chloro-N,N-dimethyl-3-nitro-aniline 
• 133360-92-6 4-amino-3-chloro-2-nitrobenzenesulphonic acid 
• 133360-91-5 2-amino-3-chloro-4-nitrobenzenesulphonic acid 
• 15945-25-2 2-chloro-3-nitrobenzenesulfonyl chloride 
• 77623-74-6 2-chloro-1-isothiocyanato-3-nitrobenzene 
• 3970-37-4 1-bromo-2-chloro-3-nitrobenzene 
• 15945-26-3 bis(2-chloro-3-nitrophenyl)disulfide 
• 120286-70-6 7-amino-8-benzylaminoquinoline 
• 120286-86-4 8-benzylamino-7-nitroquinoline 
• 133360-95-9 3-chloro-2,4-dinitrobenzenesulphonic acid 
• 1123-55-3 7-amino-1,3-benzothiazole 

Relevant articles and documents

Synthesis of 2-N-alkyl(aryl)amino-7-nitrobenzothiazoles

A highly efficient synthesis of 2-N-alkyl(aryl)amino-7-nitrobenzothiazoles has been developed. The key step involves intramolecular cyclization of a thiourea facilitated by the nitro group. A highly efficient synthesis of 2-N-alkyl(aryl)amino-7-nitrobenzothiazoles has been developed. The key step involves intramolecular cyclization of a thiourea facilitated by the nitro group.

Design, synthesis and herbicidal activity study of aryl 2,6-disubstituted sulfonylureas as potent acetohydroxyacid synthase inhibitors

A series of sulfonylurea derivatives containing a 2,6-disubstituted aryl moiety were designed, synthesized and evaluated for their herbicidal activities. Most of these compounds showed excellent inhibitory rates against both monocotyledonous and dicotyledonous weeds, especially 10a, 10h and 10i. They exhibited equivalent or superior herbicidal efficiency than commercial chlorsulfuron at the dosage of 15?g/ha and the preliminary SAR was summarized. In order to illuminate the molecular mechanism of several potent compounds, their apparent inhibition constant (Kiapp) of Arabidopsis thaliana acetohydroxyacid synthase (AHAS) were determined and the results confirmed that these compounds were all potent AHAS inhibitors. 10i have a Kiapp of 11.5?nM, which is about 4 times as potent as chlorsulfuron (52.4?nM).

Gold supported on titania for specific monohydrogenation of dinitroaromatics in the liquid phase

Liquid-phase selective monohydrogenation of various substituted dinitroaromatics to the corresponding valuable nitroanilines was investigated on gold-based catalysts. Special attention was paid to the effect of Au particle size on this monoreduction reaction. Interestingly, TiO2 supported gold catalysts containing a relatively larger mean Au particle size (>5 nm) showed far superior chemoselectivity for specific mono-hydrogenation of dinitroaromatics, with the highest performance attainable for the catalyst bearing Au particles of ca. 7.5 nm. Results in the intermolecular competitive hydrogenation showed that the intrinsic higher accumulation rates of the desired nitroanilines associated with the catalyst possessing larger Au particles were responsible for the high chemoselectivity observed. the Partner Organisations 2014.

Convenient chlorination of some special aromatic compounds using N-chlorosuccinimide

Some chlorinated aromatic compounds, including indole, benzofuran, carbazole, pyridine and aniline derivatives, are difficult to obtain through convenient chlorination. We herein report their efficient synthesis through chlorination with N-chlorosuccinimide (NCS). Optimization of the reaction conditions, including the temperature and the choice of solvent, was also investigated. This approach, which is characterized by a facile procedure, comparatively high yields and environmentally friendly features, provides a straightforward and inexpensive route to several chlorinated aromatic compounds. Georg Thieme Verlag Stuttgart · New York.

Heteromeric double helix formation by cross-hybridization of chloro-and fluoro-substituted quinoline oligoamides

Oligoamides of 8-chloroquinoline have been synthesized and shown to assemble into double helical dimers both in solution and in the solid state, and to undergo cross-hybridization with 8-fluoroquinoline oligoamide analogues; the handedness of these double

FUSED PYRIMIDINE DERIVATIVE AND USES THEREOF

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