397247-79-9

Upstream product

• 1886-67-5 N-tosyldichloromethanimine 
• 397247-69-7 2-[2-amino-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-4-methoxy-7-azaindole 
• 110-87-2 3,4-dihydro-2H-pyran 
• 122379-63-9 4-methoxy-1H-pyrrolo<2,3-b>pyridine 
• 397247-65-3 2-(1-hydroxy-2-phthalimidoethyl)-4-methoxy-7-azaindole 
• 397247-67-5 4-methoxy-2-[2-phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole 

Downstream Products

• 397247-85-7 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-88-0 5-iodo-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-90-4 5-(2-aminopyrimidin-4-yl)-4-hydroxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-89-1 5-(2-acetylaminopyrimidin-4-yl)-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-82-4 6,7-dihydro-6-hydroxy-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 

Relevant academic research and scientific papers

Synthesis of variolin B

The total synthesis of variolin B from 4-methoxy-7-azaindole is described. The preparation of the protected amino derivative 10 and a coupling reaction of the iodo derivative 12 with 2-acetylamino-4-trimethylstannylpyrimidine are the key steps of the sequ

Total Syntheses of Variolin B and Deoxyvariolin B1

Two alternative synthetic routes have been developed for the preparation of variolin B and deoxyvariolin B. The strategy is based on the preparation of the core tricyclic ring common to all variolins, pyrido[3′,2′ :4,5]pyrrolo[1,2-c]pyrimidine, followed b