3973-06-6

Basic information

• Product Name: 6-[[(benzyloxy)-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• Synonyms: 6-[[(benzyloxy)-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;6-[[1,3-Dioxo-2-phenyl-2-(phenylmethoxy)propyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;6-(((Benzyloxy)-1,3-dioxo-2-phenylpropyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid;Einecs 223-600-6
• CAS NO: 3973-06-6
• Molecular Formula: C₂₄H₂₄N₂O₆S
• Molecular Weight: 468.52216
• EINECS: 223-600-6
• Mol File: 3973-06-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 757.6°Cat760mmHg
• Flash Point: 412°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 3.99E-24mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 6-[[(benzyloxy)-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[[(benzyloxy)-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid(3973-06-6)
• EPA Substance Registry System: 6-[[(benzyloxy)-1,3-dioxo-2-phenylpropyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid(3973-06-6)

Safety Data

• Hazardous Substances Data: 3973-06-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C24H24N2O6S/c1-24(2)18(22(29)30)26-20(28)17(21(26)33-24)25-19(27)16(15-11-7-4-8-12-15)23(31)32-13-14-9-5-3-6-10-14/h3-12,16-18,21H,13H2,1-2H3,(H,25,27)(H,29,30)/t16?,17-,18+,21-/m1/s1

Upstream product

• 551-16-6 6-Aminopenicillanic Acid 
• 25774-02-1 monobenzyl phenylmalonate 

Relevant articles and documents

Preparation, hydrolysis, and oral absorption of alpha-carboxy esters of carbenicillin.

Twelve alpha-carboxy esters of carbenicillin, a parenteral broad spectrum semisynthetic penicillin, were synthesized and examined as potential oral carbenicillin derivatives. The rates at which the esters were hydrolyzed in vitro to carbenicillin by animal and human tissues were compared and the carbenicillin serum levels arising after oral administration of the esters were measured in squirrel monkeys and human volunteer subjects. The alpha-carboxyphenyl ester of carbenicillin [carfecillin (British Pharmacopoeia approved name), BRL 3475] WAS SELECTED FOR FURTHER STUDY AND IS PRESENTLY UNDERGOING CLInical trial.