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397330-60-8

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397330-60-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 397330-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,7,3,3 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 397330-60:
(8*3)+(7*9)+(6*7)+(5*3)+(4*3)+(3*0)+(2*6)+(1*0)=168
168 % 10 = 8
So 397330-60-8 is a valid CAS Registry Number.

397330-60-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-pyridyl propargyl sulfide

1.2 Other means of identification

Product number -
Other names 2-propargylthiopyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:397330-60-8 SDS

397330-60-8Downstream Products

397330-60-8Relevant articles and documents

Electrolytic partial fluorination of organic compounds. Part 57: Regioselective anodic monofluorination of nitrogen-containing heterocyclic propargyl sulfides

Riyadh, Sayed M,Ishii, Hideki,Fuchigami, Toshio

, p. 8817 - 8821 (2001)

Anodic fluorination of various nitrogen-containing heterocyclic propargyl sulfides using Et4NF·nHF (n=3,4) or Et3N·3HF as a supporting electrolyte and fluoride ion source in dimethoxyethane provided the corresponding monofluorinated products in moderate yields. Fluorination took place selectively at the position α to the sulfur atom of the sulfides and the heterocyclic moieties were not fluorinated at all.

In vitro and in vivo evaluation of organometallic gold(i) derivatives as anticancer agents

García-Moreno, Elena,Tomás, Alejandro,Atrián-Blasco, Elena,Gascón, Sonia,Romanos, Eduardo,Rodriguez-Yoldi, Jesus M.,Cerrada, Elena,Laguna, Mariano

, p. 2462 - 2475 (2016)

Alkyne gold(i) derivatives with the water soluble phosphanes PTA (1,3,5-triaza-7-phosphaadamantane) and DAPTA (3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane) were described and their anticancer potential against the colon cancer cell line Caco-2 (PD7 and TC7 clones) was studied. Strong antiproliferative effects are found, for all the new complexes, to be even more pronounced than for the reference drug cisplatin, and similar to auranofin. The interaction of these derivatives with bovine serum albumin (BSA) was studied by fluorescence spectroscopy. The types of quenching and binding constants were determined by a fluorescence quenching method. Moderate values of the binding constants are calculated for the tested derivatives indicating that these complexes can be stored and carried easily by this protein in the body. The study of the thermodynamic parameters in the case of [Au(CCCH2Spyridine)(PTA)] points out to the presence of van der Waals interactions or hydrogen bonding between the metallic complex and the protein. In addition, the complex [Au(CCCH2Spyridine)(PTA)] has shown inhibition in colon cancer proliferation of HTC-116-luc2 cell lines via the apoptotic pathway and S-phase arrest of the cell cycle. Intraperitoneal injection of this derivative in athymic nude mice inoculated with HTC-116-luc2 cells prolonged their survival and displayed moderate inhibition of the tumour growth with no subsequent organ (kidney and liver) damage after treatment.

Platinum(II) alkynyl complexes containing N- and S-propargylated ligands: Synthesis, structures and formation of PtII/AgI coordination compounds

Mohr, Fabian,Mendia, Aranzazu,Laguna, Mariano

, p. 3115 - 3123 (2008/02/13)

Alkylation of 2-hydroxypyridine, 2-pyridinethiol, 2-hydroxy-4- methylquinoline, phthalimide and pyrazole with propargyl bromide gave a series of alkynes in high yield. These alkynes were reacted with the chloroplatinum(II) compounds trans-[PtCl2(PPh3)2] and cis-[PtCl2(dppe)] to afford the respective trans- and cis-bis(alkynyl)platinum(II) complexes, which were characterised by spectroscopic analysis and by X-ray diffraction. The platinum(II) complexes containing the thiopyridyl- and pyrazolyl-substituted alkynes react with 1 or 2 equiv. of [Ag(NO3)(PPh3)] to give dimetallic Pt II/AgI complexes. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

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