3975-08-4Relevant academic research and scientific papers
Sequential and tandem oxidation/acetalization procedures for the direct generation of acetals from alcohols
Smith, Brendan M.,Graham, Andrew E.
, p. 4891 - 4894 (2008/02/08)
Alcohols are transformed directly into either acyclic or cyclic acetals in both tandem and sequential oxidation/acetalization processes using manganese dioxide, trialkyl orthoformates and catalytic quantities of indium triflate.
Soluble and polymer-supported 2- and 3-benzylated furans for the preparation of α,β-ethylenic carbonyl compounds
Albert, Sébastien,Soret, Adrien,Blanco, Luis,Deloisy, Sandrine
, p. 2888 - 2900 (2007/10/03)
Soluble and polymer-supported 2- and 3-benzylated furans were subjected to a sequence involving a Diels-Alder reaction with α,β-acetylenic carbonyl compounds, a Michael addition, and a subsequent retro-Diels-Alder reaction to yield olefinic compounds. On solid support, this traceless strategy is advantageous since pure compounds were released in the thermal cycloreversion step. The fur-2-ylated resin allowed a highly diastereoselective synthesis.
Metal-organic frameworks exhibiting strong anion-π interactions
Gural'skiy, Il'ya A.,Solntsev, Pavlo V.,Krautscheid, Harald,Domasevitch, Konstantin V.
, p. 4808 - 4810 (2007/10/03)
Coordination frameworks of pyridazino[4,5-d]pyridazine reveal a pronounced ability for anion-π interactions. The Royal Society of Chemistry 2006.
Large scale synthesis of acetylene dicarboxaldehyde mono and diacetal
Akué-Gédu, Rufine,Rigo, Beno?t
, p. 1829 - 1832 (2007/10/03)
An easy, high yield, large scale, and atom economical, synthesis of the valuable acetylene dicarboxaldehyde dimethyl and tetramethyl acetals was described starting from 2,5-dimethoxy-2,5-furan.
VERSATILITE DE REACTIVITE DE L'ACETYLENE DICARBALDEHYDE ET DES ALDEHYDES α-ACETYLENIQUES A L'EGARD DES DIENES CONJUGUES CYCLIQUES ET HETEROCYCLIQUES EN MILIEU ACIDE
Gorgues, A.,Simon, A.,Coq, A. Le,Hercouet, A.,Corre, F.
, p. 351 - 370 (2007/10/02)
The preparation of acetylenedicarbaldehyde 1 and the corresponding mono acetal 2 is described.A comparison of their reactivity with other α-acetylenic aldehydes RCCCHO 3 to 9 towards conjugated cyclic or heterocyclic dienes is presented.Under neutral conditions, the only expected Diels-Alder adducts I are formed.Under acidic conditions (HCO2H, CF3CO2H or eventually AcOH) they afford the only Diels-Alder adduct I when the cyclodiene does not present any aromatic character, and, on the opposite case, the Michael adducts II with more or less important amounts of I; starting from furan, a third pathway could also be observed dealing with t he formation of the double electrophilic substitution compounds III.The mechanisms are discussed and particularly, a common dipolar intermediate P is suggested to account for the competitive formation of I and II.
Action d'organometalliques sur les dialkylphenylorthoformiates. Preparation facile d'acetals
Barbot, Francis,Poncini, Laurence,Randrianoelina, Benjamin,Miginiac, Philippe
, p. 4016 - 4035 (2007/10/02)
The reaction of dialkylphenylorthoformiates with organometallic compounds proceeds with a good yield, at room temperature, giving the corresponding dialkylacetals ; it allows an easy preparation of acetals which are otherwise difficult to prepare.
