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1H-Isoindole-1,3(2H)-dione, 5-hydroxy-2-(4-methoxyphenyl)-, also known as 5-hydroxy-2-(4-methoxyphenyl)-1H-isoindole-1,3(2H)-dione, is a complex organic compound with the molecular formula C15H11NO4. This chemical features a 1H-isoindole-1,3(2H)-dione core, which is a heterocyclic structure with a carbonyl group at positions 1 and 3. The molecule is further characterized by a hydroxyl group at the 5-position and a 4-methoxyphenyl group attached at the 2-position. The 4-methoxyphenyl group consists of a phenyl ring with a methoxy substituent at the para position. 1H-Isoindole-1,3(2H)-dione, 5-hydroxy-2-(4-methoxyphenyl)- is of interest in various fields, including pharmaceuticals and materials science, due to its unique structure and potential applications in the development of new drugs and other chemical products.

3975-40-4

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3975-40-4 Usage

Chemical class

Isoindole-dione derivatives

Physical appearance

White to off-white crystalline solid

Molecular weight

277.26 g/mol

Usage

Pharmaceutical and research applications, drug development, building block in organic synthesis

Value in research

Unique structure and properties make it a valuable tool for chemical and biological research.

Check Digit Verification of cas no

The CAS Registry Mumber 3975-40-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,7 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3975-40:
(6*3)+(5*9)+(4*7)+(3*5)+(2*4)+(1*0)=114
114 % 10 = 4
So 3975-40-4 is a valid CAS Registry Number.

3975-40-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-hydroxy-2-(4-methoxyphenyl)isoindole-1,3-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:3975-40-4 SDS

3975-40-4Relevant academic research and scientific papers

Development of tryptase inhibitors derived from thalidomide

Tetsuhashi, Masashi,Ishikawa, Minoru,Hashimoto, Mariko,Hashimoto, Yuichi,Aoyama, Hiroshi

experimental part, p. 5323 - 5338 (2010/09/15)

A novel series of tryptase inhibitors with a N-phenylphthalimide skeleton structurally derived from thalidomide (1) has been developed. Structure-activity relationship studies led to a potent and selective tryptase inhibitor, 2-(4-cyanophenyl)isoindole-1,3-dione-5-yl 3-(2-aminopyridin-5-yl)propanoate (7), with the IC50 value of 78 nM.

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