39751-33-2 Usage
Uses
Used in Pharmaceutical Industry:
Chloramphenicol glucuronide is used as a metabolite in the pharmaceutical industry for its potential role in understanding the metabolism and pharmacokinetics of Chloramphenicol. This knowledge can help in optimizing the drug's efficacy and safety profile.
Used in Research and Development:
In the field of research and development, chloramphenicol glucuronide is utilized as a compound for studying the mechanisms of drug metabolism, particularly glucuronidation. This can contribute to the development of new drugs with improved pharmacological properties and reduced side effects.
Used in Quality Control and Standardization:
Chloramphenicol glucuronide is employed as a reference compound in quality control and standardization processes for Chloramphenicol-containing products. It helps ensure the accuracy and reliability of analytical methods used in the pharmaceutical industry.
Used in Toxicology Studies:
In toxicology, chloramphenicol glucuronide is used as a biomarker to study the potential toxic effects of Chloramphenicol on the body. This can aid in the assessment of drug safety and the establishment of safe dosages for patients.
Used in Drug Metabolism and Pharmacokinetics:
Chloramphenicol glucuronide is used as a model compound in drug metabolism and pharmacokinetics research. It helps researchers understand how drugs are metabolized in the body and how their concentrations change over time, which is crucial for optimizing drug dosages and treatment regimens.
Check Digit Verification of cas no
The CAS Registry Mumber 39751-33-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,7,5 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 39751-33:
(7*3)+(6*9)+(5*7)+(4*5)+(3*1)+(2*3)+(1*3)=142
142 % 10 = 2
So 39751-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H20Cl2N2O11/c18-14(19)15(26)20-8(9(22)6-1-3-7(4-2-6)21(29)30)5-31-17-12(25)10(23)11(24)13(32-17)16(27)28/h1-4,8-14,17,22-25H,5H2,(H,20,26)(H,27,28)/t8-,9-,10+,11+,12-,13+,17-/m1/s1
39751-33-2Relevant academic research and scientific papers
The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: Improved practicality and broader scope
Ma, Paul,Kanizaj, Nicholas,Chan, Shu-Ann,Ollis, David L.,McLeod, Malcolm D.
supporting information, p. 6208 - 6214 (2014/08/05)
A library of steroid glucuronides was prepared using the glucuronylsynthase derived from Escherichia coli β-glucuronidase, followed by purification using solid-phase extraction. A representative range of steroid substrates were screened for synthesis on t