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4-(3-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is a complex organic compound with a molecular formula of C16H15ClNO. It is a derivative of benzo[h]quinazolin-2(1H)-one, featuring a chlorophenyl group attached to the 4-position. 4-(3-chlorophenyl)-3,4,5,6-tetrahydrobenzo[h]quinazolin-2(1H)-one is characterized by its tetrahydrobenzo[h]quinazolin-2(1H)-one core, which is a fused ring system consisting of a benzene ring and a quinazolinone ring. The presence of the chlorophenyl group introduces a halogen atom, which can significantly alter the compound's reactivity and physical properties. This chemical is of interest in the field of medicinal chemistry, potentially for its pharmacological properties, although specific applications or uses are not detailed in the provided information. The compound's structure and properties make it a candidate for further study in drug development or as a chemical intermediate in the synthesis of more complex molecules.

3977-33-1

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3977-33-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3977-33-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,7 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3977-33:
(6*3)+(5*9)+(4*7)+(3*7)+(2*3)+(1*3)=121
121 % 10 = 1
So 3977-33-1 is a valid CAS Registry Number.

3977-33-1Downstream Products

3977-33-1Relevant academic research and scientific papers

FeCl3·6H2O/TMSBr-catalyzed rapid synthesis of dihydropyrimidinones and dihydropyrimidinethiones under microwave irradiation

Zhao, Fei,Jia, Xiuwen,Li, Pinyi,Zhao, Jingwei,Huang, Jun,Li, Honglian,Li, Lin

, (2017)

An efficient and practical protocol has been developed to synthesize dihydropyrimidinones and dihydropyrimidinethiones through FeCl3 6H2O TMSBr-catalyzed three-component cyclocondensation under microwave irradiation. This approach features high yields, broad substrate scope, short reaction time, mild reaction conditions, operational simplicity and easy work-up, thus affording a versatile method for the synthesis of dihydropyrimidinones and dihydropyrimidinethiones.

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