39773-85-8

Upstream product

• 563-70-2 bromonitromethane 
• 555-16-8 4-nitrobenzaldehdye 
• 3156-41-0 1-nitro-4-[(E)-2-nitroeth-1-enyl]benzene 
• 55446-62-3 1-(1,2-dibromo-2-nitro-ethyl)-4-nitro-benzene 

Downstream Products

• 928616-64-2 1-(1-Benzenesulfonyl-2-bromo-2-nitro-ethyl)-4-nitro-benzene 
• 52260-61-4 1-Nitro-1-(p-tolylsulfonyl)-2-(phenylsulfonyl)-2-(p-nitrophenyl)-ethan 

Relevant academic research and scientific papers

A convenient synthesis of substituted 1-bromo-1-nitroalkenes

The reaction of aldehydes with bromonitromethane in the presence of tri-n-butylarsine affording substituted 1-bromo-1-nitroalkenes in good yields is described.

Research on antitumor chemotherapy: X. β Nitrostyrene and nitrovinyl derivatives

In previous work, the antitumoral cytotoxicity of β nitrostyrenes obtained by simplification of the aristolochic acid molecule was demonstrated. The effect of modifying the 3 characteristic parts of the β nitrostyrene molecule was then investigated. Results in vitro and in vivo indicate a probable mechanism of action for the β nitrostyrene and nitrovinyl compounds studied, and permit definition of the maximum simplification compatible with retention of biological activity.