39778-79-5

Upstream product

• 39778-70-6 1-phenyl-cis-bicyclo<4.2.0>octan-7-one 
• 129920-34-9 (1R^*,2S^*)-2-(methylamino)-1-phenylcyclohexane-1-ol 
• 129920-35-0 2,2-Dichloro-N-((1R,2S)-2-hydroxy-2-phenyl-cyclohexyl)-N-methyl-acetamide 
• 771-98-2 1-Phenylcyclohexene 
• 5775-23-5 1-phenylcyclohexene oxide 
• 256506-05-5 N-methyl-N-(2-phenyl-2-cyclohex-1-yl)trichloroacetamide 
• 39778-86-4 C₁₅H₁₉NO 
• 125032-11-3 α,α-dichloro-N-methyl-N-(2-phenylcyclohex-2-en-1-yl)-acetamide 

Downstream Products

• 35119-24-5 1-methyl-3a-phenyl-cis-octahydroindole 

Relevant academic research and scientific papers

Radical Cyclization of N-(Cyclohex-2-enyl)-α,α-dichloroacetamides. Stereoselective Syntheses of (+/-)-Mesembranol and (+/-)-Elwesine

Stereoselective syntheses of the Sceletium alkaloid (+/-)-mesembranol (2) and the Amaryllidaceae alkaloid (+/-)-elwesine (3) have been achieved.A key step in the syntheses involves the Bu3SnH-mediated radical cyclization of the dichloroacetamides 34 and 4

Synthesis of (+/-)-Mesembranol by Radical Cyclisation of α,α-Dichloroacetamides

(+/-)-Mesembranol was synthesised in a highly stereoselective manner using Bu3SnH mediated radical cyclisation of α,α-dichloroacetamide as the key step.

Stereoselective Preparation of Bicyclic Lactams by Copper- or Ruthenium-catalysed Cyclization of N-Allyltrichloroacetamides: A Novel Entry to Pyrrolidine Alkaloid Skeletons

Cyclization of certain N-allyltrichloroacetamides provides a stereoselective preparative method for several bicyclic lactams.

Aza-Ring Expansion of cis-Bicyclooctanones and Related Compounds. A Regiospecific Synthesis of cis-Octahydroindolones

The aza-ring expansion of a series of 1-substituted cis-bicyclooctan-7-ones and related compounds has been examined.Beckmann rearrangement of oximes of the ketones 2, 6, and 7 under acid conditions affords as the major products the corresponding octahydroisoindolones 4, 8, and 9, respectively.In contrast to the Beckmann transformation, the N-methylnitrones derived from 2, 6, and 7 on treatment with p-toluenesulfonyl chloride undergo a regio- and stereospecific rearrangement to the respective cis-octahydroindolones 13, 14, and 20.The factors responsible for controling the different regiochemistry exhibited by the Beckmann and nitrone rearrangements in cis-bicyclooctanones and analogous systems are discussed.