397843-69-5 Usage
Description
[3-(N-Isopropylaminocarbonyl)phenyl]boronic acid is a boronic acid derivative characterized by the chemical formula C12H16BNO3. It is a white to off-white solid that exhibits solubility in organic solvents but is insoluble in water. [3-(N-Isopropylaminocarbonyl)phenyl]boronic acid is recognized for its potential applications in various fields, particularly in the synthesis of pharmaceuticals and agrochemicals, as well as in the realm of medicinal chemistry research.
Uses
Used in Organic Synthesis:
[3-(N-Isopropylaminocarbonyl)phenyl]boronic acid is utilized as a building block in organic synthesis for the production of a variety of pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable component in the creation of complex organic molecules.
Used in the Suzuki-Miyaura Coupling Reaction:
In the field of organic chemistry, [3-(N-Isopropylaminocarbonyl)phenyl]boronic acid serves as a reactant in the Suzuki-Miyaura coupling reaction, a method widely recognized for its role in carbon-carbon bond formation. This reaction is pivotal in the synthesis of numerous organic compounds, including those with potential applications in the pharmaceutical industry.
Used in Medicinal Chemistry Research:
[3-(N-Isopropylaminocarbonyl)phenyl]boronic acid is being explored for its potential in the development of novel treatments for certain diseases, such as cancer. Its boronic acid functional group endows it with the capacity to form reversible covalent bonds with specific biological targets, which is of significant interest to researchers in medicinal chemistry.
Used in the Development of Novel Treatments:
In the pharmaceutical industry, [3-(N-Isopropylaminocarbonyl)phenyl]boronic acid is considered for its potential role in the development of new therapeutic agents. Its ability to interact with biological targets through reversible covalent bonding makes it a promising candidate for the creation of innovative drugs, particularly for the treatment of diseases like cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 397843-69-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,7,8,4 and 3 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 397843-69:
(8*3)+(7*9)+(6*7)+(5*8)+(4*4)+(3*3)+(2*6)+(1*9)=215
215 % 10 = 5
So 397843-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H14BNO3/c1-7(2)12-10(13)8-4-3-5-9(6-8)11(14)15/h3-7,14-15H,1-2H3,(H,12,13)
397843-69-5Relevant articles and documents
Preparation and uses of conjugated solid supports for boronic acids
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, (2008/06/13)
The invention provides novel solid supports comprising dihydroxyalkyl aminoalkyl and dihydroxyalkylaminobenzyl groups, and methods for making and using them. The supports are particularly useful for immobilizing and derivatizing functionalized boronic acids for use in solid phase synthesis, such as those used in combinatorial chemistries. The compositions and methods of the invention are also useful as scavenger solid supports, e.g., in solution-phase parallel synthesis of small molecule libraries, and for use in resin-to-resin transfer reactions via phase transfer of solid supported boronic acids under both aqueous and anhydrous conditions. The methods of the invention provide convergent solid-phase synthesis of symmetrically or unsymmetrically functionalized compounds, such as biphenyl compounds. Also provided are synthesizer devices, e.g., semiautomated parallel synthesizers.
