397844-80-3Relevant academic research and scientific papers
Facile synthesis of fluorinated 2-aryl-5,7 bisalkyl pyrazolo pyrimidines from arylalkyne nitriles
Rama Rao,Lingaiah,Ezikiel,Yadla,Shanthan Rao
, p. 275 - 280 (2007/10/03)
Synthesis of pyrazolopyrimidines from fluorine substituted arylalkynenitriles is described. Arylalkynenitriles 1a-d reacted with hydrazine to give 5-aryl-3-amino-2H-pyrazoles 2a-d. The condensation of aminopyrazoles with 1,3-dicarbonyl compounds furnished
Pyrazole-thiazole compounds, pharmaceutical compositions containing them, and methods of their use for inhibiting cyclin-dependent kinases
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, (2008/06/13)
Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit
