397883-94-2Relevant academic research and scientific papers
Synthesis of 5-amino- and 4-hydroxy-2-phenylsulfonylmethylpiperidines
Masse, Julien,Langlois, Nicole
experimental part, p. 417 - 432 (2009/09/06)
Suitable protected 5-amino- and 4-hydroxy-2-phenylsulfonylmethylpiperidines were synthesized from functionalized N-benzyloxycarbonylpiperidin-l-ones through the opening of lactam ring by methyl phenyl sulfone carbanion followed by reductive aminocyclization.
Stereoselective formal synthesis of pseudodistomin C.
Langlois, Nicole
, p. 185 - 187 (2007/10/03)
[reaction: see text] Trisubstituted benzenesulfonylmethylpiperidine 4, in which the substituents are all cis to each other, is a direct synthetic precursor of the cytotoxic marine alkaloid pseudodistomin C; it has been synthesized with total diastereosele
