39795-60-3

Usage

Uses

Used in Organic Synthesis:
5-Bromooxindole is used as a reagent in organic synthesis for its ability to facilitate the formation of new chemical compounds. Its unique structure and reactivity make it a valuable component in the creation of a wide range of organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-Bromooxindole is utilized in research for its potential as an inhibitor of certain enzymes and receptors. This property allows it to be studied for its possible therapeutic effects in treating various diseases and conditions.
Used in Medicinal Chemistry:
5-Bromooxindole plays a significant role in medicinal chemistry, where it is used as a building block in the synthesis of various biologically active compounds. Its versatility in forming different molecular structures contributes to the development of new drugs and therapeutic agents.
Used in Drug Discovery:
In the field of drug discovery, 5-Bromooxindole is employed for its potential to contribute to the discovery of new drugs. Its unique properties and reactivity make it a promising candidate for the development of innovative pharmaceuticals that can address unmet medical needs.

Upstream product

• 110-86-1 pyridine 
• 35920-23-1 acetic acid-(4-bromo-N-nitroso-anilide) 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 72437-42-4 [(4-bromophenyl)diazenyl](phenyl)methyl hydroperoxide 
• 106-37-6 1.4-dibromobenzene 
• 19524-06-2 4-bromopyridine hydrochloride 
• 75-07-0 acetaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 1120-87-2 4-bromopyridin 
• 589-87-7 1,4-bromoiodobenzene 
• 939-23-1 p-phenylpyridine 
• 160377-42-4 5-(4-bromophenyl)pyrimidine 
• 181219-01-2 4-pyridineboronic acid pinacol ester 
• 15854-87-2 4-iodopyridine 

Downstream Products

• 360564-69-8 4,7-di-n-hexyl-2,9-bis[4'-(4-pyridyl-4-phenoxy)biphenyl]-1,10-phenanthroline 
• 129013-83-8 3-(4-bromophenyl)pyridine 
• 166110-82-3 [Fe(η(5)-C5H5)(η(5)-C5H4C6H4C5H4N)] 
• 532938-95-7 [Fe(η5-C5H4-C6H4-4-C5H4N)2] 
• 1009033-87-7 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine 
• 1393711-96-0 4'-(4-pyridyl)biphenyl-4-carboxylic acid 
• 672328-12-0 (2S)-N-(cyanomethyl)-4-methyl-2-{[(R)-phenyl(4'-pyridin-4-yl-1,1'-biphenyl-4-yl)methyl]oxy}pentanamide 
• 1045332-30-6 (4-(pyridine-4-yl)phenyl)boronic acid 

Relevant academic research and scientific papers

Amorphous metal-free roomerature phosphorescent small molecules with multicolor photoluminescence via a host-guest and dual-emission strategy

Metal-free roomerature phosphorescence (RTP) materials offer unprecedented potentials for photoelectric and biochemical materials due to their unique advantages of long lifetime and low toxicity. However, the achievements of phosphorescence at ambient condition so far have been mainly focused on ordered crystal lattice or on embedding into rigid matrices, where the preparation process might bring out poor repeatability and limited application. In this research, a series of amorphous organic small molecular compounds were developed with efficient RTP emission through conveniently modifying phosphor moieties to β-cyclodextrin (β-CD). The hydrogen bonding between the cyclodextrin derivatives immobilizes the phosphors to suppress the nonradiative relaxation and shields phosphors from quenchers, which enables such molecules to emit efficient RTP emission with decent quantum yields. Furthermore, one such cyclodextrin derivative was utilized to construct a host-guest system incorporating a fluorescent guest molecule, exhibiting excellent RTP-fluorescence dual-emission properties and multicolor emission with a wide range from yellow to purple including white-light emission. This innovative and universal strategy opens up new research paths to construct amorphous metal-free small molecular RTP materials and to design organic white-light-emitting materials using a single supramolecular platform.

Visible-Light-Excited Room-Temperature Phosphorescence in Water by Cucurbit[8]uril-Mediated Supramolecular Assembly

Solid-state materials with efficient room-temperature phosphorescence (RTP) emissions have found widespread applications in materials science, while liquid or solution-phase pure organic RTP emission systems has been rarely reported, because of the nonradiative decay and quenchers from the liquid medium. Reported here is the first example of visible-light-excited pure organic RTP in aqueous solution by using a supramolecular host-guest assembly strategy. The unique cucurbit[8]uril-mediated quaternary stacking structure allows tunable photoluminescence and visible-light excitation, enabling the fabrication of multicolor hydrogels and cell imaging. The present assembly-induced emission approach, as a proof of concept, contributes to the construction of novel metal-free RTP systems with tunable photoluminescence in aqueous solution, providing broad opportunities for further applications in biological imaging, detection, optical sensors, and so forth.

Dianthracene compound containing pyridyl at tail end and application thereof

The invention provides dianthracene compounds shown in a general formula I in the specification. In the general formula I, L1 and L2 represent single bonds, substituted or unsubstituted heterocyclic aromatic groups of C2-C60 or substituted or unsubstituted hydrocarbon aromatic groups of C6-C60; L3 represents a substituted or unsubstituted heterocyclic aromatic group of C2-C60 or a substituted or unsubstituted hydrocarbon aromatic group of C6-C60; L1, L2 and L3 are shown in a formula in the specification at different time; R10, R18, R21 and R23-R28 represent hydrogen, halogen and substituted or unsubstituted alkyl or alkoxy of C1-C10. The compounds have good luminescence properties, high electron transport capacities and terrific solubility and can be used in luminescent materials, electron transport materials and hole-blocking materials in the electroluminescence field. The invention also provides an organic electroluminescence device at least comprising a pair of electrodes and organic luminescent media between the electrodes. The organic luminescent media at least comprise the dianthracene compounds.

Dianthracene compound containing pyridyl at tail end and application thereof

The invention provides dianthracene compounds shown in a general formula I in the specification. In the general formula I, L1 and L2 independently represent single bonds, substituted or unsubstituted heterocyclic aromatic groups of C2-C60 or substituted or unsubstituted hydrocarbon aromatic groups of C6-C60; L3 represents a substituted or unsubstituted heterocyclic aromatic group of C2-C60 or a substituted or unsubstituted hydrocarbon aromatic group of C6-C60; R10, R11, R12, R13, R14, R15, R16, R17, R18, R21, R23, R24, R25, R26, R27 and R28 independently represent hydrogen, halogen and substituted or unsubstituted alkyl or alkoxy of C1-C10. The compounds have good luminescence properties, high electron transport capacities and terrific solubility and can be used in luminescent materials, electron transport materials and hole-blocking materials in the electroluminescence field. The invention also provides an organic electroluminescence device at least comprising a pair of electrodes and organic luminescent media between the electrodes. The organic luminescent media at least comprise the dianthracene compounds.

Tertiary amine derivatives and organic electroluminescent device including the same

A UV-region high-energy external light source is effectively absorbed to minimize damage to organic materials in the organic electroluminescent device. 1 Is a cross-sectional view of an organic electroluminescence device according to the present invention. O-2 electrode 1 Or more organic material layers disposed between the (2) and (1) th electrodes. A capping layer is included. The organic material layer and/or the capping layer may include the 1 st amine derivative represented by Formula 3. Chemical Formula 1. Wherein each substituent in Formula 1 is as defined in the description of the invention.

Room-temperature phosphorescence of a water-soluble supramolecular organic framework

A flexible porous water-soluble supramolecular organic framework was developed, which could efficiently exhibit phosphorescence both in an aqueous phase and in a film state at room-temperature.

Diverse Multi-Functionalized Oligoarenes and Heteroarenes for Porous Crystalline Materials

A modular synthesis of multi-functionalized biphenyl, terphenyl and higher linear oligophenylene dicarboxylic acids and pyridine-terminated oligoarenes by stepwise palladium–catalyzed borylation/Suzuki–Miyaura cross-coupling reactions is described. The presence of several distinct functional groups such as azide, hydroxy, and alkyne, as well as coordinative functional end groups (carboxylic acid or pyridine) combined in a single oligoarene molecular unit at strategic positions offer an advantageous dual-utility. First, these compounds can serve as useful molecular bricks (ditopic organic linkers) in the construction of complex porous crystalline materials. Second, after the assembly into the crystalline coordination networks, orthogonal functional sites within the linker-backbone offer tremendous potential from application perspectives as they can be modified by a wide range of post-synthetic modifications including azide–alkyne click chemistry. This allows further tailoring of the supramolecular assemblies to yield novel multifunctional materials.

Two-photon fluorescent probe capable of targeting mitochondria and preparation method and application of probe

The invention discloses a two-photon fluorescent probe capable of targeting mitochondria and a preparation method and application of the probe. The structure of the two-photon fluorescent probe is shown as a formula I, wherein R represents a conjugated structure, R' represents alkyl or aryl, R'' represents hydrogen, methyl or methoxy, X represents halogen anions or bi-trifluoromethane sulfonimideanions or hexafluoro-phosphoric acid anions or tetra-fluoroboric acid anions or trifluoromethanesulfonic acid anions. The compound has stronger two-photon excitation fluorescence, a good aggregation-induced luminescence effect, a great mitochondrial targeting function and excellent photoinduced singlet oxygen generation capability.

Monoamine Oxidase (MAO-N) Whole Cell Biocatalyzed Aromatization of 1,2,5,6-Tetrahydropyridines into Pyridines

A sustainable MAO-N biocatalyzed process for the synthesis of pyridines from aliphatic tetrahydropyridines (THP) has been developed. Pyridine compounds were synthesized under mild reaction conditions and with high conversion, exploiting MAO-N whole cells as aromatizing biocatalysts. The kinetic profile of the whole cell biocatalytic transformation was finally investigated via in situ 19F NMR.

ONE STEP DIRECT ARYLATION OF COMMODITY CHEMICALS TO SPECIALTY CHEMICALS BY TANDEM CATALYTIC PLATFORM

The present invention relates to a continuous direct arylation process based on a tandem catalyst for synthesizing specialty chemicals. A method for synthesizing an aryl-aryl structure from a substrate selected from the group consisting of benzyl alcohol, benzyl amine and toluene which are low value added compounds is developed using a silver ion-containing tandem catalyst. The method is applied for synthesizing hexaphenyl arylene and can be applied for synthesizing high value added compounds (not only natural substances and chemical compounds but pharmaceutical and agricultural pesticide relative fields) directly from primary raw materials through the reaction.COPYRIGHT KIPO 2017