398456-85-4

Basic information

• Product Name: Zinc, bromo[(4-methylphenyl)methyl]-
• CAS NO: 398456-85-4
• Molecular Formula: C8H9BrZn
• Molecular Weight: 250.453
• Mol File: 398456-85-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Zinc, bromo[(4-methylphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, bromo[(4-methylphenyl)methyl]-(398456-85-4)
• EPA Substance Registry System: Zinc, bromo[(4-methylphenyl)methyl]-(398456-85-4)

Safety Data

• Hazardous Substances Data: 398456-85-4(Hazardous Substances Data)

Upstream product

• 104-81-4 4-Methylbenzyl bromide 
• 7440-66-6 zinc 

Downstream Products

• 1510826-48-8 N,N-dibenzyl-2-(9-benzyl-9H-purin-6-yl)-4-p-tolylbutanamide 
• 538-39-6 1,2-di-p-tolylethane 
• 16766-53-3 α-<2H1>p-xylene 
• 1243000-27-2 (E)-4-(4-methylphenyl)methyl-4-octene 
• 72685-34-8 3,3-dimethyl-2-(4-methylphenyl)methyl-1-butene 
• 1131428-53-9 6-(4-methylbenzyl)androsta-4,6-diene-3,17-dione 
• 1131428-73-3 3-(4-methylbenzyl)androsta-3,5-dien-17-yl acetate 
• 1131428-75-5 3-(4-methylbenzyl)androsta-3,5-dien-17-ol 
• 881687-24-7 tert-butyl-2-{[4-({(2-furylmethyl)[6-(4-methylbenzyl)pyrimidin-4-yl]amino}methyl)phenyl]thio}-2-methylpropanoate 

Relevant articles and documents

Stereoselective approach to access 3-tert-Butyl-Dimethylsiloxy-2,6-Substituted piperidines through nucleophilic addition of N,O-acetals with organozinc reagents

An efficient approach to access chiral 3-tert-butyl-dimethylsiloxy 2,6-disubstituted 6-benzyl piperidines was developed through nucleophilic addition of N,O-acetals with organozinc reagents. A number of substituted benzyl zinc reagents could react with N,

Novel preparation of N-arylmethyl-N-arylmethyleneamine N-oxides from benzylic bromides with zinc and isobutyl nitrite

Treatment of benzylic bromides with Zn and LiCl, followed by the reaction with i-butyl nitrite gave N-arylmethyl-N-arylmethyleneamine N-oxides in moderate yields. The present reaction is a novel and simple method for the preparation of nitrones from benzylic bromides, although the yields are moderate.

Access to Functionalized Quaternary Stereocenters via the Copper-Catalyzed Conjugate Addition of Monoorganozinc Bromide Reagents Enabled by N, N-Dimethylacetamide

Monoorganozinc reagents, readily obtained from alkyl bromides, display excellent reactivity with β,β-disubstituted enones and TMSCl in the presence of Cu(I) and Cu(II) salts to synthesize a variety of cyclic functionalized β-quaternary ketones in 38-99% yields and 9:1-20:1 diastereoselectivities. The conjugate addition features a pronounced improvement in DMA using monoorganozinc bromide reagents. A simple one-pot protocol that harnesses in situ generated monoorganozinc reagents delivers comparable product yields.