398487-76-8 Usage
Uses
Used in Pharmaceutical Synthesis:
1H-Indol-5-amine,4-fluoro-2-methyl-(9CI) is used as a building block in the synthesis of various pharmaceuticals and research chemicals. Its unique structure and functional groups make it a valuable component in the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry Research:
Due to its potential biological activity, 1H-Indol-5-amine,4-fluoro-2-methyl-(9CI) is of interest for medicinal chemistry applications. Researchers are exploring its interactions with biological targets and evaluating its efficacy in treating specific diseases or conditions.
However, it is important to note that further research is needed to fully understand the potential uses and effects of 1H-Indol-5-amine,4-fluoro-2-methyl-(9CI) in different applications. As our understanding of 1H-Indol-5-amine,4-fluoro-2-methyl-(9CI) grows, it may find its way into new industries and applications, expanding its utility and impact on various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 398487-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,8,4,8 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 398487-76:
(8*3)+(7*9)+(6*8)+(5*4)+(4*8)+(3*7)+(2*7)+(1*6)=228
228 % 10 = 8
So 398487-76-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9FN2/c1-5-4-6-8(12-5)3-2-7(11)9(6)10/h2-4,12H,11H2,1H3
398487-76-8Relevant academic research and scientific papers
VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY
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Page/Page column 29, (2009/04/24)
The present invention relates to VEGFR inhibitors and their use in the treatment of cell proliferative diseases such as cancer. The said derivatives may further act as HDAC inhibitors.
Quinoline derivatives having vegf inhibiting activity
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, (2008/06/13)
The invention relates to compounds of formula (I) wherein: either any one of G1, G2, G3, G4 and G5 is nitrogen and the other four are —CH—, or G1, G2, G3, G4 and G5 are all —CH—; Z is —O—, —NH—, —S—, —CH2— or a direct bond; Z is linked to any one of G1, G2, G3 and G4; n is an integer from 0 to 5; m is an integer from 0 to 3; Ra represents hydrogen or fluoro; Rb, R1 and R2 are defined herein and salt thereof, process for the preparation so such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and the use of a compound of formula I in the manufacture of a medicament for the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blodded animals. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of diseases states including cancer and rheumatoid arthritis.
