39877-73-1Relevant academic research and scientific papers
Counterion-mediated hydrogen-bonding effects: Mechanistic study of gold(I)-catalyzed enantioselective hydroamination of allenes
Kim, Ji Hye,Park, Sung-Woo,Park, Sae Rom,Lee, Sungyul,Kang, Eun Joo
supporting information; scheme or table, p. 1982 - 1986 (2011/10/31)
Two of a kind: A new type of counterion-mediated syn-addition mechanism has been presented in gold-catalyzed enantioselective hydroamination reactions with [(R)-binap(AuOPNB)2] (OPNB=para-nitrobenzoate). A combination of both hydrogen bonding and the N-Au interaction efficiently controlled the challenging enantioselectivity of allenes.
Stoichiometric cyclotrimerisation of chiral alkynes at a ruthenium centre: Preparation of optically active (η6-arene)(η4-cycloocta-1,5-diene)ruthenium(0) complexes
Pertici, Paolo,Verrazzani, Alessandra,Pitzalis, Emanuela,Caporusso, Anna Maria,Vitulli, Giovanni
, p. 246 - 253 (2007/10/03)
The chiral alkynes (S)-MeCH(R)-C≡CH, 2 (R = Et, 3-methyl-1-pentyne, a; iPr, 3,4-dimethyl-1-pentyne, b; tBu, 3,4,4-trimethyl-1-pentyne, c), containing a stereogenic centre in α position to the triple bond, react at room temperature with the complex Ru(η6-naphthalene)(η4-COD), 1, to give the corresponding optically active complexes Ru{η6-(S)-1,3,5-C6H3[CH(Me)R] 3}(η4-COD), 6, and Ru{η6-(S)-1,2,4-C6H3[CH(Me)R] 3}(η4-COD), 7, the η6-1,3,5-arene regioisomer being the prevalent product. With (S)-2a, a mixture of 6a and 7a (6a/7a = 90:10) is obtained and, with the more sterically demanding alkynes (S)-2b and (S)-2c, the regioselectivity to the corresponding complexes 6b and 6c is almost complete. This synthetic procedure does not involve the stereogenic centres on the alkynes and it proceeds with complete stereoselectivity.
