39887-65-5

Upstream product

• 7461-34-9 N-benzyl-p-chlorobenzamide 

Downstream Products

• 1218987-73-5 1-(cyclohexylamino)-2-phenyl-4-p-chlorophenylpyrimido[6,1-a]isoquinolin-5-ium chloride 
• 1218987-70-2 1-(tert-butylamino)-2-phenyl-4-p-chlorophenylpyrimido[6,1-a]isoquinolin-5-ium chloride 
• 1229610-04-1 2-(4-chloro-phenyl)-4-phenyl-quinazoline 
• 23982-86-7 1-benzyl-2-(4-chlorophenyl)-1H-benzo[d]imidazole 
• 1609460-27-6 N-benzyl-4-chloro-N′-phenylbenzimidamide 

Relevant academic research and scientific papers

Solvent/oxidant-switchable synthesis of multisubstituted quinazolines and benzimidazoles via metal-free selective oxidative annulation of arylamidines

A fast and simple divergent synthesis of multisubstituted quinazolines and benzimidazoles was developed from readily available amidines, via iodine(III)-promoted oxidative C(sp3)-C(sp2) and C(sp 2)-N bond formation in nonpolar and polar solvents, respectively. Further selective synthesis of quinazolines in polar solvent was realized by TEMPO-catalyzed sp3C-H/sp2C-H direct coupling of the amidine with K2S2O8 as the oxidant. No metal, base, or other additives were needed.

Tandem synthesis of 1-(alkylamino)-2,4-diarylpyrimido[6,1-a]isoquinolin-5-ium chlorides from isoquinoline, N-alkyl-benzimidoyl chlorides, and isocyanides

1-(Alkylamino)-2,4-diarylpyrimido[6,1-a]isoquinolin-5-ium chlorides are obtained in good yields via a tandem reaction between isoquinoline, N-alkyl-benzimidoyl chlorides and alkyl isocyanides in anhydrous acetonitrile.