398997-24-5Relevant academic research and scientific papers
Design, molecular docking and synthesis of some novel 4-acetyl-1-substituted-3,4-dihydroquinoxalin-2(1H)-one derivatives for anticonvulsant evaluation as AMPA-receptor antagonists
El-Helby, Abdel-Ghany A.,Ayyad, Rezk R. A.,El-Adl, Khaled,Sakr, Helmy,Abd-Elrahman, Ashraf A.,Eissa, Ibrahim H.,Elwan, Alaa
, p. 3030 - 3046 (2016)
A new series of 4-acetyl-1-substituted-3,4-dihydroquinoxalin-2(1H)-ones (2–13) were designed and synthesized in order to evaluate their AMPA-receptor antagonism as a potential mode of anticonvulsant activity. The structure of the synthesized compounds was
Synthesis of novel quinoxalinone derivatives by conventional and microwave methods and assessing their biological activity
Nasir, Waqar,Munawar, Munawar Ali,Ahmed, Ejaz,Sharif, Ahsan,Ahmed, Saeed,Ayub, Amjad,Khan, Misbahul Ain,Nasim, Faizul Hassan
, p. 1605 - 1614 (2012/03/26)
In this study, twenty-one arylaminoquinoxalinone derivatives were synthesized and their antibacterial activities against Staphylococci aureus, Pseudomonas aureus, Escherichia coli, Bacillus subtilis, Salmonella typhi, and Shigella pneumoniae were evaluated relative to known antibiotics; augmentin, ampicillin, and chloramphenicol. The insecticidal activities of the prepared compounds were also investigated against Tribolium castaneum using permethrin as a standard insecticide. The derivatives were synthesized using both conventional and microwave techniques. Their structures were confirmed using spectral techniques and elemental analysis.
