399017-19-7Relevant academic research and scientific papers
A convenient and highly regio and stereoselective method for the synthesis of (E)-3-alkylidene isobenzofuran-1(3H)-ones (phthalides)
Mukhopadhyay, Rupa,Kundu, Nitya G
, p. 9475 - 9480 (2007/10/03)
2-Iodobenzyl alcohol on treatment with acetylenic carbinols in the presence of a palladium catalyst and copper(I) iodide as a co-catalyst afforded disubstituted alkynes. Jones oxidation of the disubstituted alkynes led to (E)-3-alkylidene isobenzofuran-1(
A Highly Efficient Synthesis of 1-Alkylidene-1,3-Dihydroisobenzofurans and 3-Alkylidene Isobenzofuran-1(3H)-ones(phthalides through Palladium-Copper Catalysis using Acetylenic Carbinols as Synthons
Khan, M. Wahab,Kundu, Nitya G.
, p. 456 - 458 (2007/10/03)
The reaction of o-iodobenzyl alcohol with various acetylenic carbinols with a terminal acetylenic group in the presence of a palladium catalyst leads to E-1-alkylidene-1,3-dihydroisobenzofurans as the exclusive products which were converted readily to E-3
