3993-32-6Relevant academic research and scientific papers
Encapsulated molecular catalysts in polysiloxane gels: Ruthenium cluster-catalyzed isomerization of alkenes
Motoyama, Yukihiro,Abe, Motonori,Kamo, Kazuyuki,Kosako, Yusuke,Nagashima, Hideo
supporting information; experimental part, p. 5321 - 5323 (2009/03/11)
Novel ruthenium-encapsulating polysiloxane gels are prepared by treatment of polymethylhydrosiloxane with diols in the presence of (μ3, η2,η3,η5-acenaphthylene)Ru 3(CO)7, and act as reusable catalysts in the isomerization of alkenes without leakage of the catalyst species. The Royal Society of Chemistry.
Optimization and metabolic stabilization of a class of nonsteroidal glucocorticoid modulators
Link,Sorensen, Bryan K.,Patel, Jyoti,Arendsen, David,Li, Gaoquan,Swanson, Susan,Nguyen, Bach,Emery, Maurice,Grynfarb, Marlena,Goos-Nilsson, Annika
, p. 4169 - 4172 (2007/10/03)
The optimization of a series of nonsteroidal glucocorticoid modulators is reported. Potent selective GR ligands that have improved metabolic stability were discovered typified by the subnanomolar acid 12 (GR binding IC 50=0.6nM).
Regioselectivity in aromatic Claisen rearrangements
Gozzo, Fabio Cesar,Fernandes, Sergio Antonio,Rodrigues, Denise Cristina,Eberlin, Marcos Nogueira,Marsaioli, Anita Jocelyne
, p. 5493 - 5499 (2007/10/03)
Theoretical calculations and the isomeric product composition for a series of eight meta-substituted allyl aryl ethers confirm the reliability of a new 1H NMR methodology used to predict aromatic Claisen regioselectivity from ground-state confo
GLUCOCORTICOID RECEPTOR MODULATORS
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, (2008/06/13)
Compounds of formula (I) or pharmaceutically acceptable salts thereof are novel glucocorticoid receptor modulators and are useful for treating type II diabetes in a mammal.
